Transcription Factor
| Accessions: | UP00145A (UniPROBE 20160601) |
| Names: | Bar-class homeodomain protein MBH1, BarH-like 2 (Drosophila), BarH-like 2 homeobox protein, Barh1, Barhl2, Homeobox protein B-H1 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q8VIB5 |
| Description: | BarH-like 2 (Drosophila) |
| Length: | 93 |
| Pfam Domains: | 17-73 Homeobox domain |
| Sequence: (in bold interface residues) | 1 EITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQV 60 61 KTWYQNRRTKWKRQTAVGLELLAEAGNYSALQR |
| Interface Residues: | 17, 18, 19, 20, 22, 34, 58, 59, 60, 61, 62, 63, 65, 66, 69, 70, 73 |
| 3D-footprint Homologues: | 3d1n_M, 5zfz_A, 1fjl_B, 2h1k_B, 5hod_A, 1puf_A, 1ig7_A, 6a8r_A, 3cmy_A, 1mnm_C, 3lnq_A, 1jgg_B, 1nk2_P, 1zq3_P, 6m3d_C, 2lkx_A, 7q3o_C, 6es3_K, 2ld5_A, 5jlw_D, 2r5y_A, 4xrs_G, 2hos_A, 3rkq_B, 1au7_A, 5flv_I, 5zjt_E, 4cyc_A, 3a01_E, 7psx_B, 1b72_A, 3l1p_A, 2hdd_A, 3knt_A, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 1du0_A, 1puf_B, 1k61_B, 1o4x_A, 8g87_X, 4qtr_D |
| Binding Motifs: | UP00145A_1 aamAAcCAATTAAswh |
| Binding Sites: | AACAATTA AACGTTTA ACCAATTA ACCGTTTA ACTAATTA ACTAATTG AGCAATTA ATCAATTA ATCGTTTA ATTAATTG CAATTAAA CAATTAAC CCAATTAA CCAATTAG CTAATTAG CTAATTGC GACAATTA GCAATTAA GCCAATTA GGCAATTA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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