Transcription Factor

Accessions: 3kmp_B (3D-footprint 20231221)
Names: Dwarfin-A, Dwf-A, MAD homolog 1, Mad-related protein 1, mMad1, Mothers against decapentaplegic homolog 1, Mothers against DPP homolog 1, Mothers-against-DPP-related 1, SMAD 1, SMAD family member 1, SMAD1_MOUSE, SMAD1-MH1
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P70340
Length: 123
Pfam Domains: 22-122 MH1 domain
Sequence:
(in bold interface residues)
1 TSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPSNCVTIPR 60
61 SLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKR 120
121 VES
Interface Residues: 63, 65, 67, 72
3D-footprint Homologues: 6fzs_A, 6h3r_A, 5nm9_A, 5od6_A, 5mey_A
Binding Motifs: 3kmp_AB TGTCTAGaCT
Binding Sites: 3kmp_C
3kmp_D
Publications: BabuRajendran N, Palasingam P, Narasimhan K, Sun W, Prabhakar S, Jauch R, Kolatkar P.R. Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-beta effectors. Nucleic acids research 38:3477-88 (2010). [Pubmed]
Related annotations: PaperBLAST

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