Transcription Factor

Accessions: E2Fc (Athamap 20091028), T00718 (AthalianaCistrome v4_May2016)
Names: AtE2F2, E2F transcription factor-2, E2F2, E2Fc, Transcription factor E2FC, AT1G47870, T00718;
Organisms: Arabidopsis thaliana
Libraries: Athamap 20091028 1, AthalianaCistrome v4_May2016 2
1 B├╝low L, Engelmann S, Schindler M, Hehl R. AthaMap, integrating transcriptional and post-transcriptional data. Nucleic acids research 37:D983-6 (2009). [Pubmed]
2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Uniprot: Q9FV70
Notes: ecotype:Col-0, experiment type: DAP-seq, family:E2F-DP
Length: 396
Pfam Domains: 155-220 E2F/DP family winged-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MAATSNSGEDPTLSYHHRSPFRFELLQSISSSDPRYSSLTPSSTNRPFSVSQSLPNSQLS 60
61 PLISPHWDDSYSQITQKVQKSRKNHRIQLGSIANMSGGESIDIAKVIVKQESSPQNVKRV 120
121 YNKSKGGTKLLKAGKRMANGEVQNGGLNGASINCRYDSSLGLLTKKFVKLIQEAEDGTLD 180
181 LNYCAVVLEVQKRRIYDITNVLEGIGLIEKTTKNHIRWKGADNLGQKDLGDQISRLKSEV 240
241 ESMQSEESRLDDLIRERQEALRSLEEDDYCRRYMFMTEEDITSLPRFQNQTLLAIKAPTA 300
301 SYIEVPDPDEMSFPQQYRMVIRSRMGPIDVYLLSKYKGDSAETSDKLGNESDQKAPVGVD 360
361 TPSLKIVTSDTDLKADYWFESDAEVSLTDLWSNFNS
Interface Residues: 155, 191, 192, 193, 194, 196
3D-footprint Homologues: 1cf7_A, 4yo2_A, 5bpd_A, 1cf7_B
Binding Motifs: E2Fc TTCCCGCcmww
M0368 AwwwwGGCGCCAAAR
Binding Sites: E2Fc_1
E2Fc_2
E2Fc_3
E2Fc_4
E2Fc_5
Publications: Mariconti L, Pellegrini B, Cantoni R, Stevens R, Bergounioux C, Cella R, Albani D. 2002. The E2F family of transcription factors from Arabidopsis thaliana. Novel and conserved components of the retinoblastoma/E2F pathway in plants. J Biol Chem. 277:9911-9. [Pubmed]

Egelkrout EM, Mariconti L, Settlage SB, Cella R, Robertson D, Hanley-Bowdoin L. 2002. Two E2F elements regulate the proliferating cell nuclear antigen promoter differently during leaf development. Plant Cell. 14:3225-36. [Pubmed]

Stevens R, Mariconti L, Rossignol P, Perennes C, Cella R, Bergounioux C. 2002. Two E2F sites in the Arabidopsis MCM3 promoter have different roles in cell cycle activation and meristematic expression. J Biol Chem. 277:32978-84. [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research.