Transcription Factor
| Accessions: | E2Fc (Athamap 20091028), T00718 (AthalianaCistrome v4_May2016), Q9FV70 (JASPAR 2024) |
| Names: | AtE2F2, E2F transcription factor-2, E2F2, E2Fc, Transcription factor E2FC, AT1G47870, T00718;, E2FC_ARATH |
| Organisms: | Arabidopsis thaliana |
| Libraries: | Athamap 20091028 1, AthalianaCistrome v4_May2016 2, JASPAR 2024 3 1 Bulow L, Engelmann S, Schindler M, Hehl R. AthaMap, integrating transcriptional and post-transcriptional data. Nucleic acids research 37:D983-6 (2009). [Pubmed] 2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed] 3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9FV70 |
| Notes: | ecotype:Col-0, experiment type: DAP-seq, family:E2F-DP |
| Length: | 396 |
| Pfam Domains: | 155-220 E2F/DP family winged-helix DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MAATSNSGEDPTLSYHHRSPFRFELLQSISSSDPRYSSLTPSSTNRPFSVSQSLPNSQLS 60 61 PLISPHWDDSYSQITQKVQKSRKNHRIQLGSIANMSGGESIDIAKVIVKQESSPQNVKRV 120 121 YNKSKGGTKLLKAGKRMANGEVQNGGLNGASINCRYDSSLGLLTKKFVKLIQEAEDGTLD 180 181 LNYCAVVLEVQKRRIYDITNVLEGIGLIEKTTKNHIRWKGADNLGQKDLGDQISRLKSEV 240 241 ESMQSEESRLDDLIRERQEALRSLEEDDYCRRYMFMTEEDITSLPRFQNQTLLAIKAPTA 300 301 SYIEVPDPDEMSFPQQYRMVIRSRMGPIDVYLLSKYKGDSAETSDKLGNESDQKAPVGVD 360 361 TPSLKIVTSDTDLKADYWFESDAEVSLTDLWSNFNS |
| Interface Residues: | 155, 191, 192, 193, 194, 196 |
| 3D-footprint Homologues: | 4yo2_A, 1cf7_A, 1cf7_B |
| Binding Motifs: | E2Fc TTCCCGCcmww M0368 AwwwwGGCGCCAAAR MA1749.1 AwwwwGGCGCCAAAR |
| Binding Sites: | E2Fc_1 E2Fc_2 E2Fc_3 E2Fc_4 E2Fc_5 |
| Publications: | Mariconti L, Pellegrini B, Cantoni R, Stevens R, Bergounioux C, Cella R, Albani D. 2002. The E2F family of transcription factors from Arabidopsis thaliana. Novel and conserved components of the retinoblastoma/E2F pathway in plants. J Biol Chem. 277:9911-9. [Pubmed] Egelkrout EM, Mariconti L, Settlage SB, Cella R, Robertson D, Hanley-Bowdoin L. 2002. Two E2F elements regulate the proliferating cell nuclear antigen promoter differently during leaf development. Plant Cell. 14:3225-36. [Pubmed] Stevens R, Mariconti L, Rossignol P, Perennes C, Cella R, Bergounioux C. 2002. Two E2F sites in the Arabidopsis MCM3 promoter have different roles in cell cycle activation and meristematic expression. J Biol Chem. 277:32978-84. [Pubmed] Vandepoele K, Vlieghe K, Florquin K, Hennig L, Beemster GT, Gruissem W, Van de Peer Y, Inzé D, De Veylder L. Genome-wide identification of potential plant E2F target genes. Plant Physiol 139:316-28 (2005). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.