Transcription Factor

Accessions: P32043 (JASPAR 2024)
Names: Homeobox protein Hox-3.4, Homeobox protein Hox-6.2, Homeobox protein Hox-C5, HXC5_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P32043
Length: 222
Pfam Domains: 156-212 Homeobox domain
Sequence:
(in bold interface residues)
1 MSSYVANSFYKQSPNIPAYNMQTCGNYGSASEVQASRYCYGGLDLSITFPPPAPSNSLHG 60
61 VDMAANPRAHPDRPACSAAAAPGHALGRDEAAPLNPGMYSQKAARPALEERAKSSGEIKE 120
121 EQAQTGQPAGLSQPPAPPQIYPWMTKLHMSHETDGKRSRTSYTRYQTLELEKEFHFNRYL 180
181 TRRRRIEIANNLCLNERQIKIWFQNRRMKWKKDSKMKSKEAL
Interface Residues: 142, 156, 157, 158, 159, 197, 198, 200, 201, 204, 205, 208, 209, 212
3D-footprint Homologues: 5zfz_A, 6a8r_A, 2h1k_B, 1puf_A, 1fjl_B, 3cmy_A, 3d1n_M, 1zq3_P, 1jgg_B, 3lnq_A, 2lkx_A, 6m3d_C, 1nk2_P, 2ld5_A, 7q3o_C, 6es3_K, 5zjt_E, 4cyc_A, 7psx_B, 5hod_A, 3a01_E, 5jlw_D, 4xrs_G, 2hdd_A, 1b72_A, 3rkq_B, 2r5y_A, 1puf_B, 1ig7_A, 5flv_I, 2hos_A, 2xsd_C, 1e3o_C, 1le8_A, 7xrc_C, 1du0_A, 3l1p_A, 1o4x_A, 4qtr_D, 1k61_B
Binding Motifs: PH0070.1 cgmrtTAATTAatwayt
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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