Transcription Factor

Accessions: Q6DJT9 (JASPAR 2024)
Names: PLAG1_HUMAN, Pleiomorphic adenoma gene 1 protein, Zinc finger protein PLAG1
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q6DJT9
Length: 500
Pfam Domains: 34-56 Zinc finger, C2H2 type
34-56 C2H2-type zinc finger
34-56 C2H2-type zinc finger
49-75 Zinc-finger double domain
62-86 C2H2-type zinc finger
67-86 Zinc finger, C2H2 type
79-102 Zinc-finger double domain
92-114 Zinc finger, C2H2 type
92-114 C2H2-type zinc finger
120-132 C2H2-type zinc finger
121-143 Zinc finger, C2H2 type
121-143 C2H2-type zinc finger
150-172 C2H2-type zinc finger
165-196 Zinc-finger double domain
185-194 C2H2-type zinc finger
185-207 Zinc finger, C2H2 type
185-207 C2H2-type zinc finger
200-223 Zinc-finger double domain
213-236 C2H2-type zinc finger
215-236 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGER 60
61 PYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKET 120
121 FKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGV 180
181 KEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQEL 240
241 LKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQS 300
301 SGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYL 360
361 MELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPALDFSQ 420
421 LFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLHSLSA 480
481 AFTSSLSTSTTLPRFHQAFQ
Interface Residues: 5, 6, 8, 11, 15, 17, 19, 20, 23, 24, 34, 44, 45, 46, 47, 48, 50, 51, 52, 53, 54, 57, 74, 75, 76, 77, 78, 79, 80, 81, 82, 102, 103, 104, 105, 106, 108, 109, 113, 130, 131, 132, 133, 134, 135, 136, 138, 139, 141, 142, 160, 161, 162, 163, 164, 167, 173, 195, 196, 197, 198, 199, 201, 202, 203, 206, 223, 224, 225, 226, 227, 230, 234, 257, 258, 259
3D-footprint Homologues: 8ssu_A, 5kkq_D, 8ssq_A, 7w1m_H, 7eyi_G, 1ubd_C, 2kmk_A, 8cuc_F, 1tf3_A, 7y3l_A, 7n5w_A, 6jnm_A, 3uk3_C, 2gli_A, 6blw_A, 1tf6_A, 6u9q_A, 5yel_A, 6wmi_A, 5ei9_F, 1mey_C, 5und_A, 4m9v_C, 8h9h_G, 2i13_A, 6e94_A, 6a57_A, 2jpa_A, 5k5i_A, 1g2f_F, 4x9j_A, 5kl3_A, 2wbs_A, 5yj3_D, 2lt7_A, 5v3j_F, 6ml4_A, 7ysf_A, 2drp_D, 1f2i_J, 8gn3_A, 1llm_D, 7txc_E, 7y3m_I
Binding Motifs: MA0163.1 GGGGCCcwmGGGGG
Binding Sites: MA0163.1.1
MA0163.1.10
MA0163.1.11
MA0163.1.12
MA0163.1.13
MA0163.1.14
MA0163.1.15
MA0163.1.16
MA0163.1.17
MA0163.1.18
MA0163.1.2
MA0163.1.3
MA0163.1.4
MA0163.1.5
MA0163.1.6
MA0163.1.7
MA0163.1.8
MA0163.1.9
Publications: Meng X, Brodsky M.H, Wolfe S.A. A bacterial one-hybrid system for determining the DNA-binding specificity of transcription factors. Nature biotechnology 23:988-94 (2005). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.