Transcription Factor

						

			
Accessions: Q99583 (JASPAR 2024)

			
Names: bHLHd3, Class D basic helix-loop-helix protein 3, Max-binding protein MNT, MNT_HUMAN, Myc antagonist MNT, Protein ROX
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q99583
Length: 582
Pfam Domains:   222-271 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 MSIETLLEAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRM   60
  61 EAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQ  120
 121 PALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHP  180
 181 GVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECF  240
 241 ETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELK  300
 301 HELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQ  360
 361 PELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQKTPLPAPPPPPAAPA  420
 421 QTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQ  480
 481 LAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSHIAHTLSHQQVNGTAGLGPPAT  540
 541 VMAKPAVGAQVVHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA
Interface Residues: 222, 224, 225, 226, 228, 229, 232, 233, 254
3D-footprint Homologues: 7z5k_B, 1an4_A, 7f2f_B, 5v0l_A, 7rcu_E, 4h10_A, 6g1l_A, 7xq5_B, 5eyo_A, 7d8t_A, 1am9_A, 5i50_B, 8osl_P
Binding Motifs: MA0825.1 avCACGTGcy
MA0825.2 CACGTG
			
Publications: Orian A, van Steensel B, Delrow J, Bussemaker HJ, Li L, Sawado T, Williams E, Loo LW, Cowley SM, Yost C, Pierce S, Edgar BA, Parkhurst SM, Eisenman RN. Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Genes Dev 17:1101-14 (2003). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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