Transcription Factor

						

			
Accessions: dif/Rel (DrosophilaTF 1.1)

			
Names: DIF_DROME
Organisms: Drosophila melanogaster
Libraries: DrosophilaTF 1.1 1
1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed]
Uniprot: P98149
Length: 667
Pfam Domains:    80-250 Rel homology domain (RHD)
Sequence: 
(in bold interface residues)		   1 MFEEAFGDIQEIINASMELNGGATGGGSVAGAVGGGGAAHHILSQSTSLPVMPSHIPLHL   60
  61 QNQNMNQNLPEPSARSGPHLRIVEEPTSNIIRFRYKCEGRTAGSIPGMNSSSETGKTFPT  120
 121 IEVCNYDGPVIIVVSCVTSDEPFRQHPHWLVSKEEADACKSGIYQKKLPPEERRLVLQKV  180
 181 GIQCAKKLEMRDSLVERERRNIDPFNAKFDHKDQIDKINRYELRLCYQAFITVGNSKVPL  240
 241 DPIVSSPIYGKSSELTITRLCSCAATANGGDEIIMLCEKIAKDDIEVRFYETDKDGRETW  300
 301 FANAEFQPTDVFKQMAIAFKTPRYRNTEITQSVNVELKLVRPSDGATSAPLPFEYYPNPE  360
 361 LLTKHNRRVAQKTVESLKRSLMSTNLHPSKQVKTSSQYTIFSKPQIATTTPQTQVSPGMP  420
 421 LMFPGGSPNFVQDIKMENGFMDVDSQSSQCPSVERNFASPRSNCSTVDSIPPMQMGQNQT  480
 481 HLYLPDATNFTFNGNFASPSSNCSTVDSIPPFQIGQRNNHMYLPENSNFPVNGCSPTHFS  540
 541 GGSMTPINNNNNVLINNNNNDFLSQKMSAISIPPQGNFGIKQVYQQTQQFLPQLQPESIP  600
 601 YLAQSHPEQSQYQQQQQPQEQQPPADEPTQSFSDLISSSIGMAPIDTSELIQDIEAELNS  660
 661 LGIQPFK
Interface Residues: 92, 94, 95, 97, 98, 100, 101, 102, 279, 313
3D-footprint Homologues: 2ram_A, 1gji_A, 7cli_B, 1nfk_A, 2o61_A, 1a3q_A
Binding Motifs: dif/Rel GGGGAwTCCCy
			
Publications: Senger K, Armstrong G.W, Rowell W.J, Kwan J.M, Markstein M, Levine M. Immunity regulatory DNAs share common organizational features in Drosophila. Molecular cell 13:19-32 (2004). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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