Transcription Factor
| Accessions: | O60248 (JASPAR 2024) |
| Names: | Protein SOX-12, Protein SOX-15, Protein SOX-20, SOX15_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 233 |
| Pfam Domains: | 48-110 Domain of unknown function (DUF1898) 49-117 HMG (high mobility group) box |
| Sequence: (in bold interface residues) | 1 MALPGSSQDQAWSLEPPAATAAASSSSGPQEREGAGSPAAPGTLPLEKVKRPMNAFMVWS 60 61 SAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRP 120 121 RRKAKSSGAGPSRCGQGRGNLASGGPLWGPGYATTQPSRGFGYRPPSYSTAYLPGSYGSS 180 181 HCKLEAPSPCSLPQSDPRLQGELLPTYTHYLPPGSPTPYNPPLAGAPMPLTHL |
| Interface Residues: | 51, 54, 56, 57, 58, 60, 64, 75, 76, 77, 80, 118, 122 |
| 3D-footprint Homologues: | 6jrp_D, 2lef_A, 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 2gzk_A, 1j5n_A, 1hry_A, 3tq6_B, 1ckt_A |
| Binding Motifs: | MA1152.1 yywTTGTtyt MA1152.2 yywTTGT |
| Publications: | Maruyama M., Ichisaka T., Nakagawa M., Yamanaka S. Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells.. J. Biol. Chem. 280:24371-24379 (2005). [Pubmed] |
| Related annotations: | PaperBLAST |
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