Transcription Factor
| Accessions: | Q05215 (JASPAR 2024) |
| Names: | AT133, Early growth response protein 4, EGR-4, EGR4_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q05215 |
| Length: | 589 |
| Pfam Domains: | 483-507 C2H2-type zinc finger 483-507 Zinc finger, C2H2 type 500-523 Zinc-finger double domain 513-535 C2H2-type zinc finger 513-535 Zinc finger, C2H2 type 527-551 Zinc-finger double domain 541-563 C2H2-type zinc finger 541-563 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MAVARGVGSPEPAPPQLYKWGGCGLGEPGSALERRGAAARGRCGRARAPRLPDSFPRGEC 60 61 PKPGARAPRSVRCGEPLPPASPPPARPQAQRARPRAPHSRRRAMLHLSEFSEPDALLVKS 120 121 TEGCCAEPSAELPRLPARDAPAATGYPGAGDFLSWALNSCGASGDLADSCFLEGPAPTPP 180 181 PGLSYSGSFFIQAVPEHPHDPEALFNLMSGILGLAPFPGPEAAASRSPLDAPFPAGSDAL 240 241 LPGPPDLYSPDLGAAPFPEAFWEASPCAGAPSQCLYEPQLSPPDVKPGLRAPPASPALDA 300 301 VSAFKGPYAPWELLSVGAPGNCGSQGDYQAAPEARFPVIGTKIEDLLSISCPAELPAVPA 360 361 NRLYPSGAYDAFPLAPGDLGEGAEGLPGLLTPPSGEGGSSGDGGEFLASTQPQLSPLGLR 420 421 SAAAADFPKPLVADIPGSSGVAAPPVPPPPPTPFPQAKARRKGRRGGKCSTRCFCPRPHA 480 481 KAFACPVESCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKP 540 541 FACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLGLSFASL |
| Interface Residues: | 419, 420, 432, 433, 439, 440, 443, 465, 468, 471, 483, 495, 496, 497, 498, 499, 501, 502, 521, 523, 524, 525, 526, 527, 528, 529, 530, 531, 551, 552, 553, 554, 555, 556, 557, 558, 559, 562 |
| 3D-footprint Homologues: | 6ppr_B, 5v3j_F, 2kmk_A, 6jnm_A, 1tf3_A, 7n5w_A, 5kl3_A, 1ubd_C, 6u9q_A, 5ei9_F, 2jpa_A, 1mey_C, 5und_A, 7ysf_A, 1f2i_J, 8ssq_A, 7w1m_H, 6ml4_A, 2gli_A, 1g2f_F, 6blw_A, 5kkq_D, 8ssu_A, 1tf6_A, 5yel_A, 4x9j_A, 2i13_A, 8h9h_G, 7eyi_G, 6e94_A, 6wmi_A, 5k5i_A, 2lt7_A, 6a57_A, 2drp_D, 3uk3_C, 8cuc_F, 7y3l_A, 2wbs_A, 7txc_E, 1llm_D, 4m9v_C, 7y3m_I, 8gn3_A, 5yj3_D |
| Binding Motifs: | MA0733.1 yymCGCCCACGCAhwt MA0733.2 mCGCCCACGCA |
| Publications: | Swirnoff A. H., Milbrandt J. DNA-binding specificity of NGFI-A and related zinc finger transcription factors. Mol. Cell. Biol. 15:2275-2287 (1995). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.