Transcription Factor

						

			
Accessions: Q9H2W2 (JASPAR 2024)

			
Names: hMix, Homeobox protein MIXL1, Homeodomain protein MIX, Mix.1 homeobox-like protein, MIX1 homeobox-like protein 1, MIXL1_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q9H2W2
Length: 232
Pfam Domains:    87-143 Homeobox domain
Sequence: 
(in bold interface residues)		   1 MATAESRALQFAEGAAFPAYRAPHAGGALLPPPSPAAALLPAPPAGPGPATFAGFLGRDP   60
  61 GPAPPPPASLGSPAPPKGAAAPSASQRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLA  120
 121 ALTLLPESRIQVWFQNRRAKSRRQSGKSFQPLARPEIILNHCAPGTETKCLKPQLPLEVD  180
 181 VNCLPEPNGVGGGISDSSSQGQNFETCSPLSEDIGSKLDSWEEHIFSAFGNF
Interface Residues: 86, 87, 88, 89, 90, 128, 129, 131, 132, 135, 136, 139, 140, 142, 143
3D-footprint Homologues: 4j19_B, 5zfz_A, 1fjl_B, 2h1k_B, 1ig7_A, 1puf_A, 6a8r_A, 3cmy_A, 3d1n_M, 1zq3_P, 1nk2_P, 3lnq_A, 2lkx_A, 1jgg_B, 7q3o_C, 2ld5_A, 6es3_K, 2hos_A, 4cyc_A, 5flv_I, 3l1p_A, 1b72_A, 5zjt_E, 3a01_E, 5hod_A, 2hdd_A, 7psx_B, 5jlw_D, 3rkq_B, 2r5y_A, 1puf_B, 4xrs_G, 1le8_A, 2xsd_C, 7xrc_C, 1e3o_C, 6wig_A, 1du0_A, 4qtr_D, 6m3d_C
Binding Motifs: MA0662.1 wyyAATTArm
MA0662.2 yAATTA
			
Publications: Zhang H, Fraser ST, Papazoglu C, Hoatlin ME, Baron MH. Transcriptional activation by the Mixl1 homeodomain protein in differentiating mouse embryonic stem cells. Stem Cells 27:2884-95 (2009). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.