Transcription Factor
Accessions: | ZNF653 (humanC2H2ZF-ChIP Feb2015) |
Names: | ENSG00000161914, Q96CK0, ZNF653 |
Organisms: | Homo sapiens |
Libraries: | humanC2H2ZF-ChIP Feb2015 1 1 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed] |
Notes: | TF family: C2H2 experiment: ChIP-seq/MEME/B1H-RC |
Length: | 615 |
Pfam Domains: | 499-522 Zinc finger, C2H2 type 500-522 C2H2-type zinc finger 514-539 Zinc-finger double domain 528-550 C2H2-type zinc finger 528-550 Zinc finger, C2H2 type 542-565 Zinc-finger double domain 557-578 C2H2-type zinc finger 557-578 Zinc finger, C2H2 type 570-596 Zinc-finger double domain |
Sequence: (in bold interface residues) | 1 MAERALEPEAEAEAEAGAGGEAAAEEGAAGRKARGRPRLTESDRARRRLESRKKYDVRRV 60 61 YLGEAHGPWVDLRRRSGWSDAKLAAYLISLERGQRSGRHGKPWEQVPKKPKRKKRRRRNV 120 121 NCLKNVVIWYEDHKHRCPYEPHLAELDPTFGLYTTAVWQCEAGHRYFQDLHSPLKPLSDS 180 181 DPDSDKVGNGLVAGSSDSSSSGSASDSEESPEGQPVKAAAAAAAATPTSPVGSSGLITQE 240 241 GVHIPFDVHHVESLAEQGTPLCSNPAGNGPEALETVVCVPVPVQVGAGPSALFENVPQEA 300 301 LGEVVASCPMPGMVPGSQVIIIAGPGYDALTAEGIHLNMAAGSGVPGSGLGEEVPCAMME 360 361 GVAAYTQTEPEGSQPSTMDATAVAGIETKKEKEDLCLLKKEEKEEPVAPELATTVPESAE 420 421 PEAEADGEELDGSDMSAIIYEIPKEPEKRRRSKRSRVMDADGLLEMFHCPYEGCSQVYVA 480 481 LSSFQNHVNLVHRKGKTKVCPHPGCGKKFYLSNHLRRHMIIHSGVREFTCETCGKSFKRK 540 541 NHLEVHRRTHTGETPLQCEICGYQCRQRASLNWHMKKHTAEVQYNFTCDRCGKRFEKLDS 600 601 VKFHTLKSHPDHKPT |
Interface Residues: | 480, 481, 482, 483, 485, 486, 489, 490, 493, 510, 511, 512, 513, 514, 517, 520, 538, 539, 540, 541, 542, 545, 546, 566, 567, 568, 569, 570, 571, 572, 573, 574, 577, 596, 597, 598, 599, 600, 601, 602, 603, 604, 607 |
3D-footprint Homologues: | 1tf6_A, 5v3j_F, 6blw_A, 5yel_A, 2drp_D, 6wmi_A, 2lt7_A, 2jpa_A, 7n5w_A, 1tf3_A, 7w1m_H, 6jnm_A, 8ssu_A, 6ml4_A, 4x9j_A, 2i13_A, 8gn3_A, 5kkq_D, 5ei9_F, 1mey_C, 5kl3_A, 1f2i_J, 2kmk_A, 8ssq_A, 2gli_A, 7eyi_G, 8h9h_G, 7ysf_A, 6e94_A, 6a57_A, 1ubd_C, 7y3l_A, 3uk3_C, 8cuc_F, 1g2f_F, 5k5l_F, 1llm_D, 2wbs_A, 6u9q_A, 5k5i_A, 5und_A, 4m9v_C, 7y3m_I, 7txc_E, 5yj3_D |
Binding Motifs: | ZNF653_ChIP mwTwwrwGTCGGmrGayaawAAwt |
Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.