Transcription Factor

Accessions: UP00133A (UniPROBE 20160601)
Names: caudal type homeo box 2, Caudal-type homeobox protein 2, Cdx-2, Cdx2, Homeobox protein CDX-2
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P43241
Description: caudal type homeo box 2
Length: 93
Pfam Domains: 18-73 Homeobox domain
Sequence:
(in bold interface residues)
1 KPAQQSLGSQVKTRTKDKYRVVYTDHQRLELEKEFHFSRYITIRRKSELAATLGLSERQV 60
61 KIWFQNRRAKERKIKKKQQQQQQQQQQQPPQPP
Interface Residues: 12, 14, 17, 18, 19, 20, 58, 59, 61, 62, 65, 66, 69, 70, 71, 73
3D-footprint Homologues: 2lkx_A, 1puf_A, 3lnq_A, 1jgg_B, 1nk2_P, 6es3_K, 7q3o_C, 2ld5_A, 7psx_B, 5jlw_D, 4xrs_G, 3cmy_A, 2hdd_A, 5zfz_A, 3rkq_B, 2r5y_A, 6m3d_C, 5flv_I, 2hos_A, 1fjl_B, 4cyc_A, 1ig7_A, 6a8r_A, 3a01_E, 2h1k_B, 1e3o_C, 1au7_A, 7xrc_C, 2xsd_C, 1le8_A, 1le8_B, 1du0_A, 1mnm_C, 1puf_B, 1k61_B, 3d1n_M, 5zjt_E, 1zq3_P, 6wig_A, 1b72_A, 5hod_A, 3l1p_A, 1o4x_A, 8g87_X, 4qtr_D
Binding Motifs: UP00133A_1 drvgGymATAAAayky
Binding Sites: TAATAAAA
AATAAAAT
AATAAACC
ACCATAAA
ATAATAAA
ATCATAAA
ATTTATGA
ATTTATGG
ATTTATTA
CAATAAAA
CAATAAAC
CCATAAAA
GCAATAAA
GCAATTAA
GCCATAAA
GTCATAAA
GTCGTAAA
GTTTATTA
TCAATAAA
TCATAAAA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.