Transcription Factor
| Accessions: | BARHL2_full (HumanTF 1.0) |
| Names: | BARH2_HUMAN, BARHL2 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Uniprot: | Q9NY43 |
| Notes: | Ensembl ID: ENSG00000143032; Full protein sequence; TF family: homeodomain; Clone source: Megaman |
| Length: | 388 |
| Pfam Domains: | 233-289 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MTMEGASGSSFGIDTILSSASSGSPGMMNGDFRPLGEARTADFRSQATPSPCSEIDTVGT 60 61 APSSPISVTMEPPEPHLVADATQHHHHLHHSQQPPPPAAAPTQSLQPLPQQQQPLPPQQP 120 121 PPPPPQQLGSAASAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAVHE 180 181 SFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFS 240 241 DHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAE 300 301 AGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRV 360 361 LIHGLGPGGQPALNPLSSPIPGTPHPR* |
| Interface Residues: | 233, 234, 235, 236, 237, 274, 275, 277, 278, 281, 282, 285, 286, 289, 308 |
| 3D-footprint Homologues: | 1puf_B, 3d1n_M, 5zfz_A, 1fjl_B, 2h1k_B, 5hod_A, 1puf_A, 1ig7_A, 6a8r_A, 3cmy_A, 1jgg_B, 1nk2_P, 1zq3_P, 6m3d_C, 3lnq_A, 2lkx_A, 1mnm_C, 6es3_K, 2ld5_A, 7q3o_C, 4xrs_G, 2hos_A, 4cyc_A, 1au7_A, 5flv_I, 3l1p_A, 5zjt_E, 4j19_B, 3a01_E, 7psx_B, 1b72_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 1k61_B, 1o4x_A, 4qtr_D, 1du0_A |
| Binding Motifs: | BARHL2_full_1 vhTAAAyGrt BARHL2_full_2 syTAAwtGsy BARHL2_full_3 TAAwyGbysyTAAwyG |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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