Transcription Factor
| Accessions: | P20293 (JASPAR 2024) |
| Names: | BRAC_MOUSE, Brachyury protein, Protein T, T-box transcription factor T, TBXT_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 436 |
| Pfam Domains: | 44-219 T-box |
| Sequence: (in bold interface residues) | 1 MSSPGTESAGKSLQYRVDHLLSAVESELQAGSEKGDPTERELRVGLEESELWLRFKELTN 60 61 EMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVTADNHRWKYVNGEWVPGGKPEPQAP 120 121 SCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQR 180 181 MITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNDHKDVMEEPGDCQQPG 240 241 YSQWGWLVPGAGTLCPPASSHPQFGGSLSLPSTHGCERYPALRNHRSSPYPSPYAHRNSS 300 301 PTYADNSSACLSMLQSHDNWSSLGVPGHTSMLPVSHNASPPTGSSQYPSLWSVSNGTITP 360 361 GSQTAGVSNGLGAQFFRGSPAHYTPLTHTVSAATSSSSGSPMYEGAATVTDISDSQYDTA 420 421 QSLLIASWTPVSPPSM |
| Interface Residues: | 69, 196, 197, 213, 216, 217 |
| 3D-footprint Homologues: | 1xbr_B, 6f59_B, 2x6v_A, 4a04_B, 1h6f_B, 5flv_I |
| Binding Motifs: | MA0009.1 CTAGGTGTGAA |
| Binding Sites: | MA0009.1.1 / MA0009.1.15 / MA0009.1.16 / MA0009.1.17 / MA0009.1.18 / MA0009.1.19 MA0009.1.10 / MA0009.1.11 / MA0009.1.12 / MA0009.1.13 / MA0009.1.14 / MA0009.1.4 / MA0009.1.5 / MA0009.1.6 / MA0009.1.7 / MA0009.1.8 MA0009.1.2 MA0009.1.20 MA0009.1.3 / MA0009.1.9 |
| Publications: | Kispert A., Herrmann B. G. The Brachyury gene encodes a novel DNA binding protein. EMBO J. 12:3211-3220 (1993). [Pubmed] |
| Related annotations: | PaperBLAST |
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