Transcription Factor
Accessions: | GATA1_MOUSE (HOCOMOCO 10), P17679 (JASPAR 2024) |
Names: | Eryf1, Erythroid transcription factor, GATA-1, GATA-binding factor 1, GATA1_MOUSE, GF-1, NF-E1 DNA-binding protein |
Organisms: | Mus musculus |
Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Length: | 413 |
Pfam Domains: | 204-237 GATA zinc finger 258-291 GATA zinc finger |
Sequence: (in bold interface residues) | 1 MDFPGLGALGTSEPLPQFVDSALVSSPSDSTGFFSSGPEGLDAASSSTSPNAATAAASAL 60 61 AYYREAEAYRHSPVFQVYPLLNSMEGIPGGSPYASWAYGKTALYPASTVCPSHEDAPSQA 120 121 LEDQEGKSNNTFLDTLKTERLSPDLLTLGTALPASLPVTGSAYGGADFPSPFFSPTGSPL 180 181 SSAAYSSPKFHGSLPLAPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRP 240 241 LIRPKKRMIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYFKLHQVNRPLTMRKD 300 301 GIQTRNRKASGKGKKKRGSNLAGAGAAEGPAGGFMVVAGSSSSGNCGEVASGLALGTAGT 360 361 AHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTTSFPTGPAPTTSSTSVIAPLSS |
Interface Residues: | 213, 214, 216, 226, 230, 267, 268, 270, 280, 284, 285, 288, 305, 307, 308 |
3D-footprint Homologues: | 3vd6_C, 4hc9_A, 3dfx_B, 1gat_A, 4gat_A |
Binding Motifs: | MA0035.2 rsWGATAAgrr MA0035.3 tyCTTATCTsy GATA1_MOUSE.H10MO.A|M01117 rsAGATAAgrr MA0035.1 sGATgs |
Binding Sites: | MA0035.3.1 MA0035.3.10 MA0035.3.11 MA0035.3.12 MA0035.3.13 MA0035.3.14 MA0035.3.15 MA0035.3.16 MA0035.3.17 MA0035.3.18 MA0035.3.19 MA0035.3.2 MA0035.3.20 MA0035.3.3 MA0035.3.4 MA0035.3.5 MA0035.3.6 MA0035.3.7 MA0035.3.8 MA0035.3.9 |
Publications: | Merika M., Orkin S. H. DNA-binding specificity of GATA family transcription factors. Mol. Cell. Biol. 13:3999-4010 (1993). [Pubmed] Orkin S.H. GATA-binding transcription factors in hematopoietic cells. Blood 80:575-81 (1992). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.