Transcription Factor

Accessions: T098502_1.02 (CISBP 1.02), P22809 (JASPAR 2024)
Names: bap, T098502_1.02;, BAGP_DROME, Homeobox protein bagpipe, Homeobox protein NK-3
Organisms: Drosophila melanogaster
Libraries: CISBP 1.02 1, JASPAR 2024 2
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P22809
Notes: experiment type:PBM, family:Homeodomain
Length: 382
Pfam Domains: 176-232 Homeobox domain
Sequence:
(in bold interface residues)
1 MLNMESAGVSAAMAGLSKSLTTPFSINDILTRSNPETRRMSSVDSEPEPEKLKPSSDRER 60
61 SISKSPPLCCRDLGLYKLTQPKEIQPSARQPSNYLQYYAAAMDNNNHHHQATGTSNSSAA 120
121 DYMQRKLAYFGSTLAAPLDMRRCTSNDSDCDSPPPLSSSPSESPLSHDGSGLSRKKRSRA 180
181 AFSHAQVFELERRFAQQRYLSGPERSEMAKSLRLTETQVKIWFQNRRYKTKRKQIQQHEA 240
241 ALLGASKRVPVQVLVREDGSTTYAHMAAPGAGHGLDPALINIYRHQLQLAYGGLPLPQMQ 300
301 MPFPYFYPQHKVPQPIPPPTQSSSFVTASSASSSPVPIPIPGAVRPQRTPCPSPNGQMMS 360
361 VESGAESVHSAAEDVDENVEID
Interface Residues: 175, 176, 177, 178, 179, 217, 218, 220, 221, 224, 225, 228, 229, 231, 232, 260
3D-footprint Homologues: 4j19_B, 1puf_A, 6a8r_A, 3cmy_A, 3d1n_M, 1fjl_B, 5zfz_A, 2h1k_B, 3lnq_A, 2lkx_A, 1jgg_B, 1nk2_P, 1zq3_P, 6m3d_C, 7q3o_C, 6es3_K, 2ld5_A, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 4xrs_G, 2hos_A, 4cyc_A, 1b72_A, 5flv_I, 3l1p_A, 1ig7_A, 5zjt_E, 3a01_E, 7psx_B, 1e3o_C, 1au7_A, 7xrc_C, 2xsd_C, 1le8_A, 4qtr_D, 1mnm_C, 1puf_B, 1k61_B, 1o4x_A, 8g87_X, 1le8_B, 1du0_A, 5hod_A
Binding Motifs: MA0211.1 TTAAGTR
M1095_1.02 ctTAAGTRsyt
Binding Sites: MA0211.1.1
MA0211.1.10
MA0211.1.11
MA0211.1.12 / MA0211.1.7
MA0211.1.13
MA0211.1.14 / MA0211.1.18
MA0211.1.15 / MA0211.1.2
MA0211.1.16
MA0211.1.17
MA0211.1.19
MA0211.1.20
MA0211.1.3
MA0211.1.4
MA0211.1.5
MA0211.1.6 / MA0211.1.9
MA0211.1.8
Publications: Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed]
Related annotations: PaperBLAST

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