Transcription Factor
| Accessions: | T144616_1.02 (CISBP 1.02), Q04890 (JASPAR 2024) |
| Names: | Sox12, T144616_1.02;, SOX12_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:Sox |
| Length: | 314 |
| Pfam Domains: | 40-108 HMG (high mobility group) box 41-97 Domain of unknown function (DUF1898) |
| Sequence: (in bold interface residues) | 1 MVQQRGARAKRDGGPPPPGPGPAAEGAREPGWCKTPSGHIKRPMNAFMVWSQHERRKIMD 60 61 QWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADYPDYKYRPRKKSKGAPA 120 121 KARPRPPGGGGGGSRLKPGPQLPGRGGRRASGGPLGGGAAAPEDDDEDEEEELLEVRLLE 180 181 TPGRELWRMVPAGRAARGPAERAQGPSGEGAAASAASPTLSEDEEPEEEEEEAATAEEGE 240 241 EETVVSGEEPLGFLSRMPPGPAGLDCSALDRDPDLLPPSGTSHFEFPDYCTPEVTEMIAG 300 301 DWRSSSIADLVFTY |
| Interface Residues: | 42, 45, 47, 48, 51, 55, 66, 67, 68, 71, 109, 113, 123 |
| 3D-footprint Homologues: | 4y60_C, 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 3tq6_B, 1hry_A |
| Binding Motifs: | PB0062.1 twATTGTTcthawh PB0166.1 mmwyasACAAAGrawt M1594_1.02 ywTTGTyyyt |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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