Transcription Factor
Accessions: | CART1_DBD (HumanTF 1.0) |
Names: | ALX homeobox protein 1, ALX1_HUMAN, CART-1, CART1, Cartilage homeoprotein 1 |
Organisms: | Homo sapiens |
Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
Uniprot: | Q15699 |
Notes: | Ensembl ID: ENSG00000180318; DNA-binding domain sequence; TF family: homeodomain; Clone source: MGC |
Length: | 116 |
Pfam Domains: | 29-85 Homeobox domain 52-81 Homeobox KN domain |
Sequence: (in bold interface residues) | 1 SPVKGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQ 60 61 LALRTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQ |
Interface Residues: | 28, 29, 30, 31, 32, 70, 71, 73, 74, 77, 78, 81, 82, 85 |
3D-footprint Homologues: | 4j19_B, 2h1k_B, 1puf_A, 3cmy_A, 1fjl_B, 6a8r_A, 3d1n_M, 1ig7_A, 5zfz_A, 1jgg_B, 6m3d_C, 3lnq_A, 2lkx_A, 1nk2_P, 1zq3_P, 7q3o_C, 6es3_K, 2ld5_A, 5flv_I, 5zjt_E, 2hdd_A, 7psx_B, 1au7_A, 5hod_A, 3rkq_B, 2r5y_A, 1puf_B, 2hos_A, 1b72_A, 5jlw_D, 4cyc_A, 4xrs_G, 3l1p_A, 3a01_E, 1e3o_C, 1le8_A, 2xsd_C, 7xrc_C, 8g87_X, 4qtr_D, 4xrm_B, 1o4x_A, 1du0_A |
Binding Motifs: | CART1_DBD hTAAyyyAATTAr |
Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
Related annotations: | PaperBLAST |
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