Transcription Factor
| Accessions: | FOSL2 (SMILE-seq 1.0) |
| Names: | Alternative protein FOSL2, cDNA: FLJ23306 fis, clone HEP11541, FOS-like antigen 2, isoform CRA_a, FOSL2, Putative uncharacterized protein FLJ23306, Q9H5M2_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | SMILE-seq 1.0 1 1 Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed] |
| Uniprot: | Q9H5M2 |
| Notes: | TF family: bZIP |
| Length: | 325 |
| Pfam Domains: | 122-181 bZIP transcription factor 124-176 Basic region leucine zipper |
| Sequence: (in bold interface residues) | 1 MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDL 60 61 QWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLS 120 121 PEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKL 180 181 EFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDK 240 241 AQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESC 300 301 SKAHRRSSSSGDQSSDSLNSPTLLA |
| Interface Residues: | 130, 131, 134, 135, 137, 138, 141, 142, 145 |
| 3D-footprint Homologues: | 4eot_A, 7x5e_E, 7x5e_F, 2wt7_A, 2wt7_B, 1skn_P, 1nwq_C, 6mg1_B, 2dgc_A, 5vpe_C, 5vpe_D |
| Binding Motifs: | FOSL2 rTGAsTcA FOSL2_2 rTGACGTCAy JUNB_FOSL2_1 krTGAsTCAy JUNB_FOSL2_2 krTGACGTCAym JUND_FOSL2_1 krTGAsTCAy JUND_FOSL2_2 kkrTkACGTCAycgc JUN_FOSL2_1 kkrTGAGTCAym JUN_FOSL2_2 grTGACGTmAt |
| Publications: | Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed] |
| Related annotations: | PaperBLAST |
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