Transcription Factor
| Accessions: | RHOXF1 (HT-SELEX2 May2017), Q8NHV9 (JASPAR 2024) |
| Names: | ENSG00000101883, RHOXF1, Ovary-, testis- and epididymis-expressed gene protein, Paired-like homeobox protein PEPP-1, Rhox homeobox family member 1, RHXF1_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1, JASPAR 2024 2 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8NHV9 |
| Notes: | TF family: Homeodomain experiment: HT-SELEX Hamming distance: 1 cycle: 2, TF family: Homeodomain experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 2 |
| Length: | 184 |
| Pfam Domains: | 104-160 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MARSLVHDTVFYCLSVYQVKISPTPQLGAASSAEGHVGQGAPGLMGNMNPEGGVNHENGM 60 61 NRDGGMIPEGGGGNQEPRQQPQPPPEEPAQAAMEGPQPENMQPRTRRTKFTLLQVEELES 120 121 VFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANELRADPDDCVY 180 181 IVVD |
| Interface Residues: | 104, 105, 106, 107, 145, 146, 148, 149, 152, 153, 156, 157, 159, 160 |
| 3D-footprint Homologues: | 1puf_A, 1fjl_B, 6a8r_A, 3d1n_M, 1ig7_A, 5zfz_A, 2lkx_A, 1nk2_P, 1zq3_P, 2ld5_A, 2h1k_B, 1jgg_B, 5flv_I, 3lnq_A, 5zjt_E, 3cmy_A, 2hdd_A, 7psx_B, 1au7_A, 5hod_A, 3rkq_B, 2r5y_A, 1puf_B, 2hos_A, 7q3o_C, 1b72_A, 5jlw_D, 4cyc_A, 6es3_K, 4xrs_G, 3a01_E, 1e3o_C, 1le8_A, 2xsd_C, 7xrc_C, 4j19_B, 8g87_X, 4qtr_D, 4xrm_B, 3l1p_A, 1o4x_A, 1du0_A, 6m3d_C |
| Binding Motifs: | MA0719.1 wTrAkCCm RHOXF1_2 gGGATCAr RHOXF1_methyl_1 gGGATyAr MA0719.2 TrAkCC |
| Publications: | Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.