Transcription Factor
| Accessions: | P97458 (JASPAR 2024) |
| Names: | Homeobox protein prophet of Pit-1, Pituitary-specific homeodomain factor, PROP-1, PROP1_MOUSE |
| Organisms: | Mus musculus, Mus spec. |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 223 |
| Pfam Domains: | 67-123 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MEAQRRSHQEKQTKGHACGRSLPEPRVASGTLISTVDRSSEAYRRLSGTELGRPKLCPQR 60 61 GRPHSRRRHRTTFNPAQLEQLESAFGRNQYPDIWAREGLAQDTGLSEARIQVWFQNRRAK 120 121 QRKQERSLLQPIAHLSTATFSGFLPESSAYPYTYGTPPPPAPCFPHPYSHSLPSQPSTAA 180 181 SLALPPQPEDWYPTLHPAPTGHLPCPPPPPMFPLSLETPKSWN |
| Interface Residues: | 39, 40, 41, 44, 45, 51, 55, 66, 67, 68, 69, 70, 108, 109, 111, 112, 115, 116, 119, 120, 123, 126, 127 |
| 3D-footprint Homologues: | 2xsd_C, 7xrc_C, 4j19_B, 1ig7_A, 2h1k_B, 1puf_A, 5zfz_A, 1mnm_C, 3cmy_A, 1fjl_B, 6a8r_A, 3d1n_M, 1jgg_B, 3lnq_A, 2lkx_A, 1nk2_P, 1zq3_P, 7q3o_C, 1le8_B, 6es3_K, 2ld5_A, 1k61_B, 2hos_A, 5jlw_D, 4cyc_A, 4xrs_G, 3l1p_A, 3a01_E, 2h8r_B, 6m3d_C, 5flv_I, 1puf_B, 5zjt_E, 1au7_A, 2hdd_A, 7psx_B, 5hod_A, 3rkq_B, 2r5y_A, 1b72_A, 1e3o_C, 1le8_A, 1o4x_A, 1du0_A, 8g87_X, 4qtr_D, 4xrm_B |
| Binding Motifs: | PH0153.1 cgmrTTAATTAAkwdac |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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