Transcription Factor
Accessions: | Q02650 (JASPAR 2024) |
Names: | B-cell-specific transcription factor, BSAP, Paired box protein Pax-5, PAX5_MOUSE |
Organisms: | Mus musculus |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Length: | 391 |
Pfam Domains: | 16-140 'Paired box' domain 282-390 Paired-box protein 2 C terminal |
Sequence: (in bold interface residues) | 1 MDLEKNYPTPRTIRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60 61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA 120 121 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 180 181 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV 240 241 FERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLTSPTPADIGSSVPGPQSYP 300 301 IVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF 360 361 PNPGLLGSPYYYSPAARGAAPPAAATAYDRH |
Interface Residues: | 29, 61, 62, 64, 66, 67, 83, 86, 89, 131, 132, 133, 134, 136, 137, 140 |
3D-footprint Homologues: | 1k78_A, 1pdn_C, 6pax_A |
Binding Motifs: | MA0014.1 drvkcasygrwGcRkrrCsr |
Binding Sites: | MA0014.1.1 MA0014.1.10 MA0014.1.11 MA0014.1.12 MA0014.1.2 MA0014.1.3 MA0014.1.4 MA0014.1.5 MA0014.1.6 MA0014.1.7 MA0014.1.8 MA0014.1.9 |
Publications: | Czerny T., Schaffner G., Busslinger M. DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site. Genes Dev. 7:2048-2061 (1993). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.