Transcription Factor

Accessions: Q02650 (JASPAR 2024)
Names: B-cell-specific transcription factor, BSAP, Paired box protein Pax-5, PAX5_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 391
Pfam Domains: 16-140 'Paired box' domain
282-390 Paired-box protein 2 C terminal
Sequence:
(in bold interface residues)
1 MDLEKNYPTPRTIRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRV 60
61 SHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLA 120
121 ERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYS 180
181 ISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRV 240
241 FERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLTSPTPADIGSSVPGPQSYP 300
301 IVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRF 360
361 PNPGLLGSPYYYSPAARGAAPPAAATAYDRH
Interface Residues: 29, 61, 62, 64, 66, 67, 83, 86, 89, 131, 132, 133, 134, 136, 137, 140
3D-footprint Homologues: 1k78_A, 1pdn_C, 6pax_A
Binding Motifs: MA0014.1 drvkcasygrwGcRkrrCsr
Binding Sites: MA0014.1.1
MA0014.1.10
MA0014.1.11
MA0014.1.12
MA0014.1.2
MA0014.1.3
MA0014.1.4
MA0014.1.5
MA0014.1.6
MA0014.1.7
MA0014.1.8
MA0014.1.9
Publications: Czerny T., Schaffner G., Busslinger M. DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site. Genes Dev. 7:2048-2061 (1993). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.