Transcription Factor
| Accessions: | ZNF621 (humanC2H2ZF-ChIP Feb2015) |
| Names: | ENSG00000172888, Q6ZSS3, ZNF621 |
| Organisms: | Homo sapiens |
| Libraries: | humanC2H2ZF-ChIP Feb2015 1 1 Najafabadi HS, Mnaimneh S, Schmitges FW, Garton M, Lam KN, Yang A, Albu M, Weirauch MT, Radovani E, Kim PM, Greenblatt J, Frey BJ, Hughes TR. C2H2 zinc finger proteins greatly expand the human regulatory lexicon. Nat Biotechnol 33:555-62 (2015). [Pubmed] |
| Notes: | TF family: C2H2;KRAB experiment: ChIP-seq/MEME/B1H-RC |
| Length: | 439 |
| Pfam Domains: | 11-50 KRAB box 151-173 C2H2-type zinc finger 151-173 C2H2-type zinc finger 151-173 Zinc finger, C2H2 type 166-190 Zinc-finger double domain 179-192 C2H2-type zinc finger 179-201 C2H2-type zinc finger 197-214 Zinc-finger double domain 206-227 C2H2-type zinc finger 207-229 Zinc finger, C2H2 type 207-229 C2H2-type zinc finger 221-245 Zinc-finger double domain 234-257 C2H2-type zinc finger 235-257 Zinc finger, C2H2 type 235-257 C2H2-type zinc finger 250-273 Zinc-finger double domain 262-283 C2H2-type zinc finger 281-302 Zinc-finger double domain 291-313 Zinc finger, C2H2 type 291-301 C2H2-type zinc finger 291-313 C2H2-type zinc finger 308-329 Zinc-finger double domain 318-341 C2H2-type zinc finger 319-341 C2H2-type zinc finger 319-341 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MLQTTWPQESVTFEDVAVYFTQNQWASLDPAQRALYGEVMLENYANVASLVAFPFPKPAL 60 61 ISHLERGEAPWGPDPWDTEILRGISQGGESWIKNEGLVIKQEASEETELHRMPVGGLLRN 120 121 VSQHFDFKRKALKQTFNLNPNLILRGGMKFYECKECGKIFRYNSKLIRHQMSHTGEKPFK 180 181 CKECGKAFKSSYDCIVHEKNHIGEGPYECKECGKGLSSNTALTQHQRIHTGEKPYECKEC 240 241 GKAFRRSAAYLQHQRLHTGEKLYKCKECWKAFGCRSLFIVHQRIHTGEKPYQCKECGKAF 300 301 TQKIASIQHQRVHTGEKPYECKVCGKAFKWYGSFVQHQKLHPVEKKPVKVLGPSLVSPQC 360 361 SSPAIPPVLLQGSCSASAVAVPSLTFPHAVLIPTSGNFFMLLPTSGIPSSSAQIVRVFQG 420 421 LTPTVKPSPVILTPSSHSS |
| Interface Residues: | 139, 141, 142, 145, 161, 162, 163, 164, 165, 168, 171, 189, 190, 192, 193, 196, 217, 218, 219, 220, 221, 223, 224, 225, 226, 227, 230, 235, 245, 246, 247, 248, 249, 250, 251, 252, 253, 255, 256, 273, 274, 275, 276, 277, 279, 280, 301, 302, 303, 304, 305, 307, 308, 329, 330, 331, 332, 333, 335, 336, 340 |
| 3D-footprint Homologues: | 5v3j_F, 7n5w_A, 8ssu_A, 2i13_A, 8gn3_A, 7eyi_G, 8h9h_G, 8ssq_A, 7ysf_A, 1tf3_A, 7w1m_H, 5und_A, 1tf6_A, 6blw_A, 1mey_C, 5yel_A, 3uk3_C, 5yj3_D, 5k5i_A, 1llm_D, 2wbs_A, 5ei9_F, 7txc_E, 5kl3_A, 1f2i_J, 4m9v_C, 6e94_A, 6a57_A, 2jpa_A, 2kmk_A, 2gli_A, 6ml4_A, 4x9j_A, 5kkq_D, 2drp_D, 6wmi_A, 1ubd_C, 6jnm_A, 1g2f_F, 5k5l_F, 6u9q_A, 2lt7_A, 7y3m_I, 8cuc_F, 7y3l_A |
| Binding Motifs: | ZNF621_ChIP aaarkCcCAGGGmAG |
| Related annotations: | PaperBLAST |
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