Transcription Factor

Accessions: sna (DrosophilaTF 1.1), P08044 (JASPAR 2024)
Names: SNAI_DROME
Organisms: Drosophila melanogaster
Libraries: DrosophilaTF 1.1 1, JASPAR 2024 2
1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: P08044
Length: 390
Pfam Domains: 245-269 C2H2-type zinc finger
279-302 C2H2-type zinc finger
280-302 C2H2-type zinc finger
280-302 Zinc finger, C2H2 type
294-317 Zinc-finger double domain
307-324 C2H2-type zinc finger
307-328 C2H2-type zinc finger
307-328 Zinc finger, C2H2 type
321-344 Zinc-finger double domain
334-356 Zinc finger, C2H2 type
334-356 C2H2-type zinc finger
334-356 C2H2-type zinc finger
348-373 Zinc-finger double domain
362-380 C2H2-type zinc finger
362-385 Zinc finger, C2H2 type
362-385 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MAANYKSCPLKKRPIVFVEERLPQTEALALTKDSQFAQDQPQDLSLKRGRDEETQDYQQP 60
61 EPKRDYVLNLSKTPERNSSSSSNSCLLSPPVEAQDYLPTEIHMRGLTAGTTGYTTATPTT 120
121 INPFQSAFVMAAGCNPISALWSSYQPHLAAFPSPASSMASPQSVYSYQQMTPPSSPGSDL 180
181 ETGSEPEDLSVRNDIPLPALFHLFDEAKSSSSGASVSSSSGYSYTPAMSASSASVAANHA 240
241 KNYRFKCDECQKMYSTSMGLSKHRQFHCPAAECNQEKKTHSCEECGKLYTTIGALKMHIR 300
301 THTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFQCPDCPRSFADRSNLRAHQQTHVDVK 360
361 KYACQVCHKSFSRMSLLNKHSSSNCTITIA
Interface Residues: 232, 234, 235, 255, 256, 258, 259, 262, 290, 291, 292, 293, 294, 296, 297, 299, 300, 303, 316, 317, 318, 319, 320, 322, 323, 324, 344, 345, 346, 347, 348, 349, 350, 351, 352, 355, 372, 373, 374, 375, 376, 377, 378, 379, 383
3D-footprint Homologues: 2i13_A, 7w1m_H, 5v3j_F, 1ubd_C, 6jnm_A, 8ssu_A, 6ml4_A, 5kkq_D, 5ei9_F, 5kl3_A, 8ssq_A, 7eyi_G, 7ysf_A, 6wmi_A, 6a57_A, 2jpa_A, 8cuc_F, 7y3l_A, 7n5w_A, 3uk3_C, 1tf3_A, 2gli_A, 1g2f_F, 1tf6_A, 4x9j_A, 1llm_D, 6blw_A, 2wbs_A, 6u9q_A, 1mey_C, 1f2i_J, 5k5i_A, 2kmk_A, 5und_A, 4m9v_C, 8h9h_G, 2lt7_A, 7y3m_I, 6e94_A, 5k5l_F, 8gn3_A, 5yel_A, 7txc_E, 2drp_D, 5yj3_D
Binding Motifs: sna vwrACAGGTGymc
MA0086.1 CAGGTG
MA0086.2 kbrACAGGTGyaa
MA0086.3 rACAGGTGy
Binding Sites: sna_1
sna_10
sna_11
sna_12
sna_13
sna_14
sna_15
sna_16
sna_17
sna_18
sna_19
sna_2
sna_20
sna_21
sna_22
sna_23
sna_24
sna_25
sna_26
sna_27
sna_28
sna_29
sna_3
sna_30
sna_31
sna_32
sna_33
sna_34
sna_35
sna_36
sna_37
sna_38
sna_39
sna_4
sna_40
sna_5
sna_6
sna_7
sna_8
sna_9
MA0086.1.1
MA0086.1.10
MA0086.1.11
MA0086.1.12
MA0086.1.13
MA0086.1.14
MA0086.1.15
MA0086.1.16
MA0086.1.17
MA0086.1.18
MA0086.1.19
MA0086.1.2
MA0086.1.20
MA0086.1.3
MA0086.1.4
MA0086.1.5
MA0086.1.6
MA0086.1.7
MA0086.1.8
MA0086.1.9
Publications: Mauhin V., Lutz Y., Dennefeld C., Alberga A. Definition of the DNA-binding site repertoire for the Drosophila transcription factor SNAIL. Nucleic Acids Res. 21:3951-3957 (1993). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.