Transcription Factor

Accessions: Q99594 (JASPAR 2024)
Names: DTEF-1, TEA domain family member 3, TEAD-3, TEAD3_HUMAN, Transcriptional enhancer factor TEF-5
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q99594
Length: 435
Pfam Domains: 8-427 TEA/ATTS domain family
Sequence:
(in bold interface residues)
1 MASNSWNASSSPGEAREDGPEGLDKGLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL 60
61 SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQVGIKAMNLDQVSKD 120
121 KALQSMASMSSAQIVSASVLQNKFSPPSPLPQAVFSTSSRFWSSPPLLGQQPGPSQDIKP 180
181 FAQPAYPIQPPLPPTLSSYEPLAPLPSAAASVPVWQDRTIASSRLRLLEYSAFMEVQRDP 240
241 DTYSKHLFVHIGQTNPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFW 300
301 ADLNSTIQEGPGAFYGVSSQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVY 360
361 RIHRSPMCEYMINFIHKLKHLPEKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVST 420
421 SEHGAQHHVYKLVKD
Interface Residues: 66, 70, 87, 88, 91, 92, 95, 96, 99
3D-footprint Homologues: 5gzb_A, 5no6_N
Binding Motifs: MA0808.1 rCATTCCw
Publications: Wasserman W.W, Fickett J.W. Identification of regulatory regions which confer muscle-specific gene expression. Journal of molecular biology 278:167-81 (1998). [Pubmed]
Related annotations: PaperBLAST

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