Transcription Factor
| Accessions: | O08961 (JASPAR 2024) |
| Names: | Olf1/EBF-associated zinc finger protein, rOAZ, Smad- and Olf-interacting zinc finger protein, Zinc finger protein 423, ZN423_RAT |
| Organisms: | Rattus norvegicus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | O08961 |
| Length: | 1311 |
| Pfam Domains: | 74-99 C2H2-type zinc finger 146-168 C2H2-type zinc finger 146-168 Zinc finger, C2H2 type 161-185 Zinc-finger double domain 174-196 C2H2-type zinc finger 190-212 Zinc-finger double domain 202-224 Zinc finger, C2H2 type 202-224 C2H2-type zinc finger 216-241 Zinc-finger double domain 230-252 C2H2-type zinc finger 230-252 Zinc finger, C2H2 type 230-266 C2H2 type zinc-finger (2 copies) 230-253 Zinc-finger of C2H2 type 230-254 C2H2-type zinc finger 272-294 C2H2-type zinc finger 331-353 C2H2-type zinc finger 436-460 C2H2-type zinc finger 507-530 C2H2-type zinc finger 544-569 C2H2-type zinc finger 545-567 C2H2-type zinc finger 659-682 C2H2-type zinc finger 659-681 C2H2-type zinc finger 690-711 C2H2-type zinc finger 691-711 C2H2-type zinc finger 719-742 C2H2-type zinc finger 719-740 Zinc finger, C2H2 type 719-737 C2H2-type zinc finger 719-738 Zinc-finger of C2H2 type 747-770 C2H2-type zinc finger 808-830 C2H2-type zinc finger 957-979 C2H2-type zinc finger 957-981 C2H2-type zinc finger 958-979 Zinc-finger of C2H2 type 971-995 Zinc-finger double domain 988-1008 C2H2-type zinc finger 1090-1106 C2H2-type zinc finger 1146-1177 C2H2 type zinc-finger (2 copies) 1147-1168 C2H2-type zinc finger 1148-1167 Zinc-finger of C2H2 type 1148-1170 C2H2-type zinc finger 1225-1236 C2H2-type zinc finger 1256-1279 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MSRRKQAKPRSVKVEEGEASDFSLAWDSSVAAAGGLEGESECDRKSSRALEDRNSVTSQE 60 61 ERNEDDEDVEDESIYTCDHCQQDFESLADLTDHRAHRCPGDGDDDPQLSWVASSPSSKDV 120 121 ASPTQMIGDGCDLGLGEEEGGTGLPYPCQFCDKSFIRLSYLKRHEQIHSDKLPFKCTFCS 180 181 RLFKHKRSRDRHIKLHTGDKKYHCHECEAAFSRRDHLKIHLKTHSSSKPFKCSVCKRGFS 240 241 STSSLQSHMQAHKKNKEHLAKSEKEAKKDDFMCDYCEDTFSQTEELEKHVLTLHPQLSEK 300 301 ADLQCIHCPEVFVDESTLLAHIHQAHANQKHKCPMCPEQFSSVEGVYCHLDSHRQPDSSN 360 361 HSVSPDPVLGSVASMSSATPDSTPDPVLGSVASMSSATPDSSASVERGSTPDSTLKPLRG 420 421 QKKMRDDGQSWSKVVYSCPYCSKRDFTSLAVLEIHLKTIHADKPQQSHTCQICLDSMPTL 480 481 YNLNEHVRKLHKSHAYPVMQFGNISAFHCNYCPEMFADINSLQEHIRVSHCGPNANPPDG 540 541 NNAFFCNQCSMGFLTESSLTEHIQQAHCSVGSTKLESPVIQPTQSFMEVYSCPYCTNSPI 600 601 FGSILKLTKHIKENHKNIPLAHSKKSKAEQSPVSSDVEVSSPKRQRLSGSANSISNGEYP 660 661 CNQCDLKFSNFESFQTHLKLHLELLLRKQACPQCKEDFDSQESLLQHLTVHYMTTSTHYV 720 721 CESCDKQFSSVDDLQKHLLDMHTFVLYHCTLCQEVFDSKVSIQVHLAVKHSNEKKMYRCT 780 781 ACNWDFRKEADLQVHVKHSHLGNPAKAHKCIFCGETFSTEVELQCHITTHSKKYNCRFCS 840 841 KAFHAVLLLEKHLREKHCVFDPAAENGTANGVPPTSTKKAEPADLQGMLLKNPEAPNSHE 900 901 ASEDDVDASEPMYGCDICGAAYTMEVLLQNHRLRDHNIRPGEDDGSRKKAEFIKGSHKCN 960 961 VCSRTFFSENGLREHLQTHRGPAKHYMCPICGERFPSLLTLTEHKVTHSKSLDTGTCRIC 1020 1021 KMPLQSEEEFIEHCQMHPDLRNSLTGFRCVVCMQTVTSTLELKIHGTFHMQKLAGSSAAS 1080 1081 SPNGQGLQKLYKCALCLKEFRSKQDLVRLDVNGLPYGLCAGCMARSANGQVGGLAPPEPA 1140 1141 DRPCAGLRCPECNVKFESAEDLESHMQVDHRDLTPETSGPRKGAQTSPVPRKKTYQCIKC 1200 1201 QMTFENEREIQIHVANHMIEEGINHECKLCNQMFDSPAKLLCHLIEHSFEGMGGTFKCPV 1260 1261 CFTVFVQANKLQQHIFAVHGQEDKIYDCSQCPQKFFFQTELQNHTMSQHAQ |
| Interface Residues: | 146, 156, 157, 158, 159, 160, 162, 163, 164, 165, 166, 167, 169, 184, 185, 186, 187, 188, 189, 191, 192, 195, 212, 213, 214, 215, 216, 218, 219, 241, 242, 243, 244, 246, 247, 251, 271, 272, 281, 282, 283, 284, 285, 287, 288, 292, 314, 315, 316, 317, 320, 323, 354, 733, 758, 760, 761, 819, 821, 822, 825, 845, 848, 849, 877, 878, 967, 968, 969, 970, 972, 973, 997, 999, 1000 |
| 3D-footprint Homologues: | 2kmk_A, 6jnm_A, 8ssq_A, 7w1m_H, 5und_A, 8ssu_A, 6ml4_A, 5v3j_F, 6blw_A, 5kkq_D, 1ubd_C, 5ei9_F, 1mey_C, 4m9v_C, 2lt7_A, 1tf6_A, 2i13_A, 6e94_A, 7ysf_A, 6wmi_A, 6a57_A, 2jpa_A, 7n5w_A, 5k5i_A, 2gli_A, 1g2f_F, 4x9j_A, 8gn3_A, 2wbs_A, 6u9q_A, 7txc_E, 5kl3_A, 7eyi_G, 8h9h_G, 1tf3_A, 8cuc_F, 7y3l_A, 3uk3_C, 5yj3_D, 5k5l_F, 1llm_D, 1f2i_J, 7y3m_I, 5yel_A, 2drp_D |
| Binding Motifs: | MA0116.1 gsmmCCyWrGGkkkm |
| Binding Sites: | MA0116.1.1 / MA0116.1.2 / MA0116.1.3 / MA0116.1.4 / MA0116.1.5 / MA0116.1.6 / MA0116.1.7 / MA0116.1.8 / MA0116.1.9 MA0116.1.10 MA0116.1.11 MA0116.1.12 MA0116.1.13 / MA0116.1.14 MA0116.1.15 / MA0116.1.16 / MA0116.1.17 / MA0116.1.18 / MA0116.1.19 / MA0116.1.20 |
| Publications: | Tsai R. Y. L., Reed R. R. Identification of DNA recognition sequences and protein interaction domains of the multiple-Zn-finger protein Roaz. Mol. Cell. Biol. 18:6447-6456 (1998). [Pubmed] |
| Related annotations: | PaperBLAST |
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