Transcription Factor

						

			
Accessions: Q99593 (JASPAR 2024)

			
Names: T-box protein 5, T-box transcription factor TBX5, TBX5_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 518
Pfam Domains:    56-237 T-box
Sequence: 
(in bold interface residues)		   1 MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHE   60
  61 RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK  120
 121 WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ  180
 181 PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD  240
 241 DMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGP  300
 301 SQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEEDSFYRSSYPQ  360
 361 QQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDR  420
 421 LPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQCGPQTGLQSPG  480
 481 TLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS
Interface Residues: 81, 215, 216, 232, 235, 236
3D-footprint Homologues: 2x6v_A, 4a04_B, 1h6f_B, 5flv_I, 1xbr_B, 6f59_B
Binding Motifs: MA0807.1 AGGTGTkA
			
Publications: Wilson V, Conlon FL. The T-box family. Genome Biol : (2002;3(6):REVIEWS3008.). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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