Transcription Factor
| Accessions: | T061561_1.02 (CISBP 1.02), P41696 (JASPAR 2024) |
| Names: | AZF1, T061561_1.02;, AZF1_YEAST |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:C2H2 ZF |
| Length: | 914 |
| Pfam Domains: | 593-615 Zinc finger, C2H2 type 593-615 C2H2-type zinc finger 607-632 Zinc-finger double domain 621-643 Zinc finger, C2H2 type 621-643 C2H2-type zinc finger 635-660 Zinc-finger double domain 649-671 Zinc finger, C2H2 type 649-671 C2H2-type zinc finger 649-668 Zinc-finger of C2H2 type 663-690 Zinc-finger double domain 677-702 Zinc finger, C2H2 type 677-702 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MPPPTAQFMGPTQAGQNESQNQSSGEAGEQNQEHGQGPTPILNQSQPASSQPQHQQQRNE 60 61 SISYYTNFNQPRYSTDASINSFLNISDNVPVTSTGGPSSGGAYSNLPRLSTSSTHQPPDL 120 121 SQIGRGFSIVNNLFPQQQQLQNQHRQQQQQQQQQSHQQPPFKTPSFSTGLTGSSSQYQFL 180 181 PRNDNTSQPPSKRNSVYLGPNDGPDFEFFSMQQSQQPQFQPSSRRESNSMRPPLLIPAAT 240 241 TKSQSNGTNNSGNMNTNADYESFFNTGTNNSNSNQNPYFLSSRNNSLKFNPEDFDFQFKR 300 301 RNSFVRGTLDHSSQNAFIPESRLNSLSVNNKANGDPVADNVTNNMKGKSNEVDNDDGNDS 360 361 SNNNNNNNNNNNNENNNDNNNDNNDNSINSATSTNIPNQEDHSLASTDTTSNSRKDLKEI 420 421 EQRLRKHLNDEDNYSSAISRPLDKNDVIEGSEGLNKHIDESGMQPNIIKKRKKDDSTVYV 480 481 KNEMPRTDPPMSKDNSTSAEGAAMANFSGKEPPIPDISSVSDDATNLIGATKVDQLMLII 540 541 QARKKGFTEKVNTTQDGDLLFNQTMDILPPKSELVGGVEKPKGTQNTRAVKKHECPYCHR 600 601 LFSQATHLEVHVRSHIGYKPFVCDYCGKRFTQGGNLRTHERLHTGEKPYSCDICDKKFSR 660 661 KGNLAAHLVTHQKLKPFVCKLENCNKTFTQLGNMKAHQNRFHKETLNALTAKLAEMNPSE 720 721 NIPLEERQLLEYFASIYKNSNRGIKGRGKGVGTKKSTISSPENHPASTILNPNTNANNAI 780 781 ANDSENNGNPEGNIDSSSNSNPGSHSMISPTQKDMGTLQSQFIQNNFNNSVNSSNPSNQP 840 841 IINYNYTTLPHSRLGSSSSSNTNNNNSNFSVGAAPGVLMAPTTNNDFSFNLDQSNDNERS 900 901 QQEQVRFKNINYKS |
| Interface Residues: | 570, 571, 572, 573, 578, 581, 603, 604, 605, 606, 607, 609, 610, 612, 613, 616, 630, 631, 632, 633, 634, 635, 637, 638, 639, 642, 659, 660, 661, 662, 663, 664, 665, 666, 667, 670, 689, 690, 691, 692, 693, 695, 696, 700 |
| 3D-footprint Homologues: | 7w1m_H, 7n5w_A, 2i13_A, 8gn3_A, 6blw_A, 5kkq_D, 5ei9_F, 1mey_C, 5kl3_A, 5k5i_A, 2kmk_A, 8ssq_A, 5und_A, 2gli_A, 1g2f_F, 5k5l_F, 8ssu_A, 1tf6_A, 6ml4_A, 5v3j_F, 4x9j_A, 8h9h_G, 7eyi_G, 7y3m_I, 6e94_A, 7ysf_A, 6wmi_A, 2lt7_A, 2jpa_A, 1ubd_C, 3uk3_C, 1tf3_A, 6jnm_A, 8cuc_F, 7y3l_A, 1llm_D, 2wbs_A, 6u9q_A, 5yel_A, 7txc_E, 1f2i_J, 5yj3_D, 4m9v_C, 6a57_A, 2drp_D |
| Binding Motifs: | M0536_1.02 rraawarraa MA0277.1 aAAARGAAa |
| Publications: | Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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