Transcription Factor
| Accessions: | T154000_1.02 (CISBP 1.02), O22921 (JASPAR 2024), T09928 (AthalianaCistrome v4_May2016) |
| Names: | T154000_1.02;, WRKY25, Probable WRKY transcription factor 25, WRK25_ARATH, WRKY DNA-binding protein 25, AT2G30250, T09928; |
| Organisms: | Arabidopsis thaliana |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2, AthalianaCistrome v4_May2016 3 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] 3 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed] |
| Notes: | experiment type:PBM, family:WRKY, ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq |
| Length: | 393 |
| Pfam Domains: | 166-223 WRKY DNA -binding domain 329-385 WRKY DNA -binding domain |
| Sequence: (in bold interface residues) | 1 MSSTSFTDLLGSSGVDCYEDDEDLRVSGSSFGGYYPERTGSGLPKFKTAQPPPLPISQSS 60 61 HNFTFSDYLDSPLLLSSSHSLISPTTGTFPLQGFNGTTNNHSDFPWQLQSQPSNASSALQ 120 121 ETYGVQDHEKKQEMIPNEIATQNNNQSFGTERQIKIPAYMVSRNSNDGYGWRKYGQKQVK 180 181 KSENPRSYFKCTYPDCVSKKIVETASDGQITEIIYKGGHNHPKPEFTKRPSQSSLPSSVN 240 241 GRRLFNPASVVSEPHDQSENSSISFDYSDLEQKSFKSEYGEIDEEEEQPEMKRMKREGED 300 301 EGMSIEVSKGVKEPRVVVQTISDIDVLIDGFRWRKYGQKVVKGNTNPRSYYKCTFQGCGV 360 361 KKQVERSAADERAVLTTYEGRHNHDIPTALRRS |
| Interface Residues: | 172, 173, 174, 176, 177, 188, 335, 336, 338, 339, 350 |
| 3D-footprint Homologues: | 6j4e_B, 6j4f_F, 6j4g_B, 6ir8_A, 7z0u_A |
| Binding Motifs: | M1685_1.02 yRGTCAAc MA1081.1 yRGTCAAc M0797 wgcGTTGACywttth M0814 aawRGTCAAMg MA1081.2 wwwwwrGTCAACGdww MA1081.3 rGTCAACG |
| Binding Sites: | MA1081.3.1 / MA1081.3.11 / MA1081.3.12 / MA1081.3.13 / MA1081.3.15 / MA1081.3.17 / MA1081.3.6 / MA1081.3.7 / MA1081.3.9 MA1081.3.18 / MA1081.3.19 / MA1081.3.4 MA1081.1.13 MA1081.1.4 MA1081.1.16 MA1081.1.14 MA1081.1.10 MA1081.1.6 MA1081.1.7 MA1081.1.1 MA1081.1.11 MA1081.1.12 MA1081.1.15 MA1081.1.17 / MA1081.1.19 MA1081.1.18 / MA1081.1.8 MA1081.1.2 MA1081.1.20 MA1081.1.3 MA1081.1.5 MA1081.1.9 MA1081.2.3 MA1081.2.8 MA1081.2.9 MA1081.2.11 MA1081.2.6 MA1081.2.13 MA1081.2.14 MA1081.2.15 MA1081.2.16 MA1081.2.18 MA1081.2.1 MA1081.2.10 MA1081.2.12 MA1081.2.17 MA1081.2.19 MA1081.2.2 MA1081.2.20 MA1081.2.4 MA1081.2.5 MA1081.2.7 MA1081.3.10 / MA1081.3.14 / MA1081.3.16 / MA1081.3.3 MA1081.3.20 MA1081.3.8 MA1081.3.2 / MA1081.3.5 |
| Publications: | Yu D, Chen C, Chen Z. 2001. Evidence for an important role of WRKY DNA binding proteins in the regulation of NPR1 gene expression. Plant Cell. 13:1527-40. [Pubmed] |
| Related annotations: | PaperBLAST |
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