Transcription Factor

						

			
Accessions: bin (DrosophilaTF 1.1), T082679_1.02 (CISBP 1.02)

			
Names: DmFoxF, Forkhead box protein biniou, Forkhead box protein FoxF, FOXF_DROME, bin, T082679_1.02;
Organisms: Drosophila melanogaster
Libraries: DrosophilaTF 1.1 1, CISBP 1.02 2
1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed]

2 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Uniprot: Q95WV0
Notes: experiment type:B1H, family:Forkhead
Length: 676
Pfam Domains:   311-406 Fork head domain
Sequence: 
(in bold interface residues)		   1 MIKSEEASDRSVMTMDQLGGYYHDPRAHPPFSHPHAHSHPHQHTHTGHPYRAGNLLTGGN   60
  61 YQAMGGGESPTELIDEKPNIGYMELKHYMDATPTATPVSAAQHYSLSALHSMGTPPASSS  120
 121 PIPPYGVLMTAHSAGSASPQSNSKTPTDLPQDLQYASSSTSTAKVQPLQVQLQPLNHQYA  180
 181 STIKYCSNNTILSANDYQLLTSQEQAGQQQPQQLPAQQLQHSPGGGYMSRISTSPSQVIS  240
 241 NAHGMPVLNYSSSSSSPAKSLNGSESSPPSQNHLENKVSGSAVVGTGGSSQQDAPSTPDT  300
 301 TKKSGTRRPEKPALSYINMIGHAIKESPTGKLTLSEIYAYLQKSYEFFRGPYVGWKNSVR  360
 361 HNLSLNECFKKLPKGMGVGKPGKGNYWTIDENSAHLFEDEGSLRRRPRGYRSKIKVKPYA  420
 421 GHANGYYASGYGDAGMDNGNYYASPAFASYDYSAAGATGVSPAGGQGFADPWNAHAAHSG  480
 481 SSSVGVGMGVGPLPQYTNISCLAAGGNVNGSATTPPLAHSALGMAPSASSSSSPLGAAAT  540
 541 LQSDYAPTASLVAAGYSYATSAGSLDNGLRSISLQQLPGLSSIQHAQAQAQAQAHHHHHQ  600
 601 HHASHPSHSHQGHGSMHQNHGTSSTTPPPSQSGGSHGIDHSPIDRKPAYLPPISPPPMMV  660
 661 ALNGGGGYYEGLKYAN
Interface Residues: 23, 25, 308, 354, 356, 357, 358, 360, 361, 362, 364, 365, 374, 383, 408
3D-footprint Homologues: 7uin_D, 7yzg_A, 7yz7_A, 7yzb_A, 7vox_H, 2hdc_A, 7vou_C, 6ako_C, 2c6y_A, 7yze_A, 7tdw_A, 3g73_A, 6el8_A, 7tdx_A, 3l2c_A, 6nce_A, 2uzk_A, 2a07_J, 7cby_C, 3co6_C, 3qrf_G
Binding Motifs: bin rTAAATA
M4765_1.02 TAAACArmGA
			
Publications: Zaffran S, Küchler A, Lee H.H, Frasch M. biniou (FoxF), a central component in a regulatory network controlling visceral mesoderm development and midgut morphogenesis in Drosophila. Genes & development 15:2900-15 (2001). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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