Transcription Factor

						

			
Accessions: FOXJ3_MOUSE (HOCOMOCO 10), Q8BUR3 (JASPAR 2024)

			
Names: FOXJ3_MOUSE
Organisms: Mus musculus
Libraries: HOCOMOCO 10 1, JASPAR 2024 2
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q8BUR3
Length: 623
Pfam Domains:    78-162 Fork head domain
Sequence: 
(in bold interface residues)		   1 MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALL   60
  61 DPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGS  120
 121 GWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTLPTRPKKRARSVERASTP  180
 181 YSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNADQDGSDSPRSSLNNSLSDQSLASV  240
 241 NLNSVGSVHSYTPVTNHPEPVSQPLTPQQQQQPQYNLPEREKQLLFTEYNFEDLSASFRS  300
 301 LYKSVFEQSLSQQGLMSIPSESSQQSHTSCSYQHSPSSTVTSHPHSNQSSLPNNHSGLSA  360
 361 TGSNSVAQVSLSHPQMHPQPSPHTPHRPHGLPQHPQRPQHPAPHPQQHSQLQPPHSQHPP  420
 421 PHQHIQHHPNHQHQTLAHQPPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVD  480
 481 LSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVPQNVCHGAMHP  540
 541 AKPSQHIGAGNLYIDSRQSLPPSVMPPPGYPHIPQALNTPGTTMAGHHGAMNQQHMMPSQ  600
 601 AFPMRRPLPPDDIQDDFDWDSIV
Interface Residues: 121, 123, 124, 125, 127, 128, 129, 131, 132, 141, 148, 169
3D-footprint Homologues: 7vox_H, 2hdc_A, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 3l2c_A, 7yzb_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 3qrf_G
Binding Motifs: PB0121.1 awbrcCmwAACAwwksw
FOXJ3_MOUSE.H10MO.A|M01105 tTGTTTATkkTTw
MA0851.1 / PB0017.1 hraarRTAAACAAwsmc
MA0851.2 RTAAACAAw
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]


Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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