Transcription Factor
| Accessions: | Q9JKQ4 (JASPAR 2024) |
| Names: | Homeodomain protein IRXB2, Iroquois homeobox protein 5, Iroquois-class homeodomain protein IRX-5, IRX5_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 484 |
| Pfam Domains: | 116-172 Homeobox domain 130-169 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 MSYPQGYLYQPSASLALYSCPAYSTSVISGPRTDELGRSSSGSAFSPYAGSTAFTAPSPG 60 61 YNSHLQYGADPAAAAAAAFSYVGSPYDHTPGMAGSLGYHPYAAPLGSYPYGDPAYRKNAT 120 121 RDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTP 180 181 RNRSEDEEEEENIDLEKNDEDEPQKPEDKGDLEGPESGGAEQKATAGCERLQGPLSPAGK 240 241 ETEGSLSDSDFKESSSEGRHDELPRPPRAGESSPAGPATARLAEDAGPHYPASVPAPGPH 300 301 PSAGELPPGSGGSSVIHSPPPPPPPPPAVLAKPKLWSLAEIATSSDKVKDGGGGSEGSPC 360 361 PPCPGPMGGQTLGGSRASPAPAPARSPSAQCPFPGGTVLSRPLYYTAPFYPGYTNYGSFG 420 421 HLHGHPGPGPSPTAGPGSHFNGLNQTVLNRADVLAKDPKMLRSQSQLDLCKDSPYELKKG 480 481 MSDI |
| Interface Residues: | 113, 115, 116, 117, 118, 119, 123, 157, 158, 160, 161, 164, 165, 168, 169, 172 |
| 3D-footprint Homologues: | 3d1n_M, 1jgg_B, 5hod_A, 3cmy_A, 1fjl_B, 5jlw_D, 2hdd_A, 2r5y_A, 1puf_B, 1ig7_A, 2hos_A, 3a01_E, 4cyc_A, 2lkx_A, 2ld5_A, 2h1k_B, 1du0_A, 1k61_B, 6fqq_E, 4xrm_B, 1puf_A, 1mnm_C, 7psx_B, 4xrs_G, 5zjt_E, 3rkq_B, 1nk2_P, 1b72_A, 5flv_I, 2d5v_B, 6fqp_B, 1o4x_A |
| Binding Motifs: | PH0086.1 wwwawACATGTwawwkw |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.