Transcription Factor

Accessions: 3fhz_B (3D-footprint 20231221)
Names: Arginine repressor, ARGR_MYCTU
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P9WPY8
Length: 161
Pfam Domains: 7-76 Arginine repressor, DNA binding domain
92-159 Arginine repressor, C-terminal domain
Sequence:
(in bold interface residues)
1 AGPEVAANRAGRQARIVAILSSAQVRSQNELAALLAAEGIEVTQATLSRDLEELGAVKLR 60
61 GADGGTGIYVVPEDGSPVRGVSGGTDRMARLLGELLVSTDDSGNLAVLRTPPGAAHYLAS 120
121 AIDRAALPQVVGTIAGDDTILVVAREPTTGAQLAGMFENLR
Interface Residues: 43, 44, 45, 46, 48, 49
3D-footprint Homologues: 2p5l_D, 3lap_B, 4u7b_B
Binding Motifs: 3fhz_BF TGAATcnnTAyTCA
Publications: Cherney L.T, Cherney M.M, Garen C.R, James M.N. The structure of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator and Co-repressor, L-arginine. Journal of molecular biology 388:85-97 (2009). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.