Transcription Factor
| Accessions: | Q8BJA3 (JASPAR 2024) |
| Names: | HMBX1_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 419 |
| Pfam Domains: | 25-228 Hepatocyte nuclear factor 1 (HNF-1), N terminus 269-339 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MLSSFPVVLLETMSHYTDEPRFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDK 60 61 FGRRSSYGGSSYGNSTNNVPASSSTATASTQTQHSGMSPSPSNSYDTSPLPCTTNQNGRE 120 121 NNDRLSTSNGKMSPSRYHANSMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAF 180 181 LANRRISQAVVAQVTGISQSRISHWLLQQGSDLSEQKKRAFYRWYQLEKTNPGATLSMRP 240 241 APIPIEDPEWRQTPPPVSATPGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEI 300 301 ANACNAVIQKPGKKLSDLERVTSLKVYNWFANRRKEIKRRANIAAILESHGIDVQSPGGH 360 361 SNSDDVDGNDYSEQDDSTSHSDHQDPISLAVEMAAVNHTILALARQGANEIKTEALDDD |
| Interface Residues: | 188, 198, 199, 200, 201, 203, 204, 211, 212, 267, 268, 270, 271, 327, 328, 331, 332, 335, 336, 337, 338, 339 |
| 3D-footprint Homologues: | 2r1j_L, 1ic8_B, 2h8r_B, 4j19_B, 1mnm_C, 3cmy_A, 1fjl_B, 1k61_B, 1puf_B, 1le8_A, 1ig7_A, 2hdd_A, 3a01_E, 1b72_A, 4xrm_B, 1du0_A, 2lkx_A, 3lnq_A, 2hos_A |
| Binding Motifs: | PH0040.1 rwrawCTRGTTAaydws |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.