Transcription Factor

Accessions: ap (DrosophilaTF 1.1), P29673 (JASPAR 2024)
Names: APTE_DROME
Organisms: Drosophila melanogaster
Libraries: DrosophilaTF 1.1 1, JASPAR 2024 2
1 Down T.A, Bergman C.M, Su J, Hubbard T.J. Large-scale discovery of promoter motifs in Drosophila melanogaster. PLoS computational biology 3:e7 (2007). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 469
Pfam Domains: 148-203 LIM domain
210-265 LIM domain
368-424 Homeobox domain
Sequence:
(in bold interface residues)
1 MGVCTEERPVMHWQQSARFLGPGAREKSPTPPVAHQGSNQCGSAAGANNNHPLFRACSSS 60
61 SCPDICDHSTKPFGNAYGTESFRSYETADRATFEDSAAKFSISRSRTDCTEVSDETTSGI 120
121 SFKTEPFGPPSSPESTSDSKITRNLDDCSGCGRQIQDRFYLSAVEKRWHASCLQCYACRQ 180
181 PLERESSCYSRDGNIYCKNDYYSFFGTRRCSRCLASISSNELVMRARNLVFHVNCFCCTV 240
241 CHTPLTKGDQYGIIDALIYCRTHYSIAREGDTASSSMSATYPYSAQFGSPHNDSSSPHSD 300
301 PSRSIVPTGIFVPASHVINGLPQPARQKGRPRKRKPKDIEAFTANIDLNTEYVDFGRGSH 360
361 LSSSSRTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLSQKTGLPKRVLQVWFQNARA 420
421 KWRRMMMKQDGSGLLEKGEGALDLDSISVHSPTSFILGGPNSTPPLNLD
Interface Residues: 368, 369, 370, 371, 409, 410, 412, 413, 416, 417, 420, 421, 423, 424
3D-footprint Homologues: 1fjl_B, 6a8r_A, 2h1k_B, 1ig7_A, 1puf_A, 3cmy_A, 5zfz_A, 3d1n_M, 1nk2_P, 3lnq_A, 2lkx_A, 1jgg_B, 1zq3_P, 6m3d_C, 2ld5_A, 7q3o_C, 6es3_K, 2hos_A, 5zjt_E, 4cyc_A, 2d5v_B, 7psx_B, 5hod_A, 3l1p_A, 1b72_A, 3a01_E, 5jlw_D, 2hdd_A, 3rkq_B, 2r5y_A, 4xrs_G, 2xsd_C, 7xrc_C, 1e3o_C, 1le8_B, 4qtr_D, 1du0_A, 4xrm_B
Binding Motifs: MA0209.1 yTAATKA
ap TAATnn
Binding Sites: MA0209.1.16
MA0209.1.12
MA0209.1.17
MA0209.1.7
MA0209.1.1
MA0209.1.10
MA0209.1.11
MA0209.1.13
MA0209.1.14
MA0209.1.15
MA0209.1.18
MA0209.1.19
MA0209.1.2
MA0209.1.20
MA0209.1.3
MA0209.1.4
MA0209.1.5
MA0209.1.6
MA0209.1.8
MA0209.1.9
Publications: Yan Shian-Jang, Gu Yi, Li Willis X., Fleming Robert J. Multiple signaling pathways and a selector protein sequentially regulate Drosophila wing development.. Development 131:285-298 (2004). [Pubmed]

Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.