Transcription Factor
| Accessions: | Q9HBU1 (JASPAR 2024) |
| Names: | BARX1_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9HBU1 |
| Length: | 254 |
| Pfam Domains: | 143-199 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MQRPGEPGAARFGPPEGCADHRPHRYRSFMIEEILTEPPGPKGAAPAAAAAAAGELLKFG 60 61 VQALLAARPFHSHLAVLKAEQAAVFKFPLAPLGCSGLSSALLAAGPGLPGAAGAPHLPLE 120 121 LQLRGKLEAAGPGEPGTKAKKGRRSRTVFTELQLMGLEKRFEKQKYLSTPDRIDLAESLG 180 181 LSQLQVKTWYQNRRMKWKKIVLQGGGLESPTKPKGRPKKNSIPTSEQLTEQERAKDAEKP 240 241 AEVPGEPSDRSRED |
| Interface Residues: | 141, 143, 144, 145, 146, 184, 185, 187, 188, 191, 192, 195, 196, 199 |
| 3D-footprint Homologues: | 1mnm_C, 1ig7_A, 5zfz_A, 1puf_A, 2h1k_B, 6a8r_A, 3cmy_A, 1fjl_B, 3d1n_M, 6m3d_C, 1jgg_B, 3lnq_A, 2lkx_A, 1nk2_P, 1zq3_P, 2ld5_A, 7q3o_C, 6es3_K, 4cyc_A, 2d5v_B, 5flv_I, 5zjt_E, 3a01_E, 7psx_B, 5hod_A, 1puf_B, 2hdd_A, 5jlw_D, 3rkq_B, 2r5y_A, 1b72_A, 4xrs_G, 2hos_A, 2xsd_C, 1e3o_C, 1au7_A, 1le8_A, 7xrc_C, 1le8_B, 1du0_A, 3l1p_A, 8g87_X, 4qtr_D, 1k61_B, 4xrm_B, 1o4x_A |
| Binding Motifs: | MA0875.1 vcmATTAr MA0875.2 cmATTA |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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