Transcription Factor
| Accessions: | ARNT_HUMAN (HOCOMOCO 10) |
| Names: | ARNT protein, ARNT_HUMAN, Aryl hydrocarbon receptor nuclear translocator, bHLHe2, Class E basic helix-loop-helix protein 2, Dioxin receptor, nuclear translocator, HIF-1-beta, HIF1-beta, Hypoxia-inducible factor 1-beta |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] |
| Length: | 789 |
| Pfam Domains: | 91-142 Helix-loop-helix DNA-binding domain 166-269 PAS fold 369-449 PAS fold 370-464 PAS domain 374-460 PAS fold |
| Sequence: (in bold interface residues) | 1 MAATTANPEMTSDVPSLGPAIASGNSGPGIQGGGAIVQRAIKRRPGLDFDDDGEGNSKFL 60 61 RCDDDQMSNDKERFARSDDEQSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCS 120 121 ALARKPDKLTILRMAVSHMKSLRGTGNTSTDGSYKPSFLTDQELKHLILEAADGFLFIVS 180 181 CETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSENALTGRILDLK 240 241 TGTVKKEGQQSSMRMCMGSRRSFICRMRCGSSSVDPVSVNRLSFVRNRCRNGLGSVKDGE 300 301 PHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQGSKFCLVAIGRLQVTSSPNCTDMSNVCQP 360 361 TEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKG 420 421 QVLSVMFRFRSKNQEWLWMRTSSFTFQNPYSDEIEYIICTNTNVKNSSQEPRPTLSNTIQ 480 481 RPQLGPTANLPLEMGSGQLAPRQQQQQTELDMVPGRDGLASYNHSQVVQPVTTTGPEHSK 540 541 PLEKSDGLFAQDRDPRFSEIYHNINADQSKGISSSTVPATQQLFSQGNTFPPTPRPAENF 600 601 RNSGLAPPVTIVQPSASAGQMLAQISRHSNPTQGATPTWTPTTRSGFSAQQVATQATAKT 660 661 RTSQFGVGSFQTPSSFSSMSLPGAPTASPGAAAYPSLTNRGSNFAPETGQTAGQFQTRTA 720 721 EGVGVWPQWQGQQPHHRSSSSEQHVQQPPAQQPGQPEVFQEMLSMLGDQSNSYNNEEFPD 780 781 LTMFPPFSE |
| Interface Residues: | 91, 93, 94, 95, 97, 98, 101, 102, 128, 616 |
| 3D-footprint Homologues: | 1a0a_B, 1an4_A, 5eyo_A, 5nj8_D, 4zpk_A, 6g1l_A, 5gnj_I, 7xi3_A, 5sy7_B, 4zpk_B, 7d8t_A, 5i50_B, 4h10_A, 5v0l_A, 4zpr_B, 1am9_A, 7ssa_L, 4h10_B, 8osl_O, 8osl_P, 5nj8_C, 7xhv_B, 7xi3_B, 5v0l_B, 3g00_B |
| Binding Motifs: | ARNT_HUMAN.H10MO.B|M01015 tyrCGTGc |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.