Transcription Factor

						

			
Accessions: Q86Y25 (JASPAR 2024)

			
Names: hKID3, Kidney, ischemia, and developmentally-regulated protein 3, Z354C_HUMAN, Zinc finger protein 354C
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 554
Pfam Domains:     12-52 KRAB box
  215-234 C2H2-type zinc finger
  216-238 C2H2-type zinc finger
  216-238 Zinc finger, C2H2 type
  231-255 Zinc-finger double domain
  243-264 C2H2-type zinc finger
  244-266 C2H2-type zinc finger
  244-266 Zinc finger, C2H2 type
  258-283 Zinc-finger double domain
  271-294 C2H2-type zinc finger
  272-294 Zinc finger, C2H2 type
  272-294 C2H2-type zinc finger
  287-310 Zinc-finger double domain
  300-322 Zinc finger, C2H2 type
  300-320 C2H2-type zinc finger
  315-338 Zinc-finger double domain
  327-343 C2H2-type zinc finger
  328-350 C2H2-type zinc finger
  345-366 Zinc-finger double domain
  355-378 C2H2-type zinc finger
  356-378 Zinc finger, C2H2 type
  356-378 C2H2-type zinc finger
  370-395 Zinc-finger double domain
  383-404 C2H2-type zinc finger
  384-406 Zinc finger, C2H2 type
  401-422 Zinc-finger double domain
  412-434 C2H2-type zinc finger
  412-432 C2H2-type zinc finger
  412-434 Zinc finger, C2H2 type
  427-450 Zinc-finger double domain
  439-460 C2H2-type zinc finger
  440-462 C2H2-type zinc finger
  440-462 Zinc finger, C2H2 type
  454-478 Zinc-finger double domain
  468-490 C2H2-type zinc finger
  468-486 C2H2-type zinc finger
  468-490 Zinc finger, C2H2 type
  483-507 Zinc-finger double domain
  495-518 C2H2-type zinc finger
  496-518 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MAVDLLSAQEPVTFRDVAVFFSQDEWLHLDSAQRALYREVMLENYSSLVSLGIPFSMPKL   60
  61 IHQLQQGEDPCMVEREVPSDTRLGFKTWLETEALPHRQDIFIEETSQGMVKKESIKDGHW  120
 121 DINFEEAVEFESEIEEEQEKKPLRQMIDSHEKTISEDGNHTSLELGKSLFTNTALVTQQS  180
 181 VPIERIPNMYYTFGKDFKQNFDLMKCFQIYPGGKPHICNECGKSFKQNLHLIEHQRIHTG  240
 241 EKPYKCNECEKTFSHRSSLLSHQRIHTGEKPYKCNECEKAFSNSSTLIKHLRVHTGEKPY  300
 301 RCRECGKAFSQCSTLTVHQRIHTGEKLYKCGECEKAFNCRAKLHRHQRIHTGEKPYKCSE  360
 361 CGKGYSQFTSLAEHQRFHTGEQLYTCLECGRTFTRIVTLIEHQRIHTGQKPYQCNECEKA  420
 421 FNQYSSFNEHRKIHTGEKLYTCEECGKAFGCKSNLYRHQRIHTGEKPYQCNQCGKAFSQY  480
 481 SFLTEHERIHTGEKLYKCMECGKAYSYRSNLCRHKKVHTKEKLYKWKEYGKPFICSSSLT  540
 541 QYQRFFKGDKAYEV
Interface Residues: 226, 227, 228, 229, 230, 232, 233, 235, 236, 237, 239, 254, 255, 256, 257, 258, 260, 261, 262, 282, 283, 284, 285, 286, 287, 288, 289, 290, 292, 293, 311, 312, 313, 314, 317, 339, 340, 341, 342, 344, 345, 366, 367, 368, 369, 370, 371, 373, 394, 395, 396, 397, 398, 401, 404, 423, 424, 425, 426, 429, 435, 449, 450, 451, 453, 454, 456, 457, 461, 478, 479, 480, 481, 482, 484, 485, 506, 507, 508, 509, 510, 513
3D-footprint Homologues: 6jnm_A, 3uk3_C, 1tf3_A, 1tf6_A, 2i13_A, 6blw_A, 5kkq_D, 5ei9_F, 2kmk_A, 7w1m_H, 7ysf_A, 6wmi_A, 6a57_A, 2jpa_A, 8cuc_F, 7n5w_A, 5und_A, 2gli_A, 1g2f_F, 4x9j_A, 1mey_C, 5kl3_A, 5yj3_D, 5k5i_A, 4m9v_C, 7eyi_G, 8h9h_G, 5yel_A, 5k5l_F, 8ssu_A, 5v3j_F, 1llm_D, 2wbs_A, 7txc_E, 1f2i_J, 8ssq_A, 7y3m_I, 6e94_A, 6ml4_A, 1ubd_C, 8gn3_A, 6u9q_A, 2lt7_A, 7y3l_A, 2drp_D
Binding Motifs: MA0130.1 mTCCAC
Binding Sites: MA0130.1.1 / MA0130.1.2
MA0130.1.10
MA0130.1.11 / MA0130.1.12
MA0130.1.13
MA0130.1.14
MA0130.1.15
MA0130.1.16
MA0130.1.3
MA0130.1.4
MA0130.1.5
MA0130.1.6
MA0130.1.7
MA0130.1.8
MA0130.1.9
			
Publications: Gao L, Sun C, Qiu H.L, Liu H, Shao H.J, Wang J, Li W.X. Cloning and characterization of a novel human zinc finger gene, hKid3, from a C2H2-ZNF enriched human embryonic cDNA library. Biochemical and biophysical research communications 325:1145-52 (2004). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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