Transcription Factor
| Accessions: | P40645 (JASPAR 2024) |
| Names: | SOX-LZ, SOX6_MOUSE, Transcription factor SOX-6 |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 827 |
| Pfam Domains: | 620-688 HMG (high mobility group) box 621-678 Domain of unknown function (DUF1898) |
| Sequence: (in bold interface residues) | 1 MSSKQATSPFACTADGEEAMTQDLTSREKEEGSDQHPASHLPLHPIMHNKPHSEELPTLV 60 61 STIQQDADWDSVLSSQQRMESENNKLCSLYSFRNTSTSPHKPDEGSREREIMNSVTFGTP 120 121 ERRKGSLADVVDTLKQKKLEEMTRTEQEDSSCMEKLLSKDWKEKMERLNTSELLGEIKGT 180 181 PESLAEKERQLSTMITQLISLREQLLAAHDEQKKLAASQIEKQRQQMDLARQQQEQIARQ 240 241 QQQLLQQQHKINLLQQQIQVQGHMPPLMIPIFPHDQRTLAAAAAAQQGFLFPPGITYKPG 300 301 DNYPVQFIPSTMAAAAASGLSPLQLQKGHVSHPQINPRLKGISDRFGRNLDPSEHGGGHS 360 361 YNHRQIEQLYAAQLASMQVSPGAKMPSTPQPPNSAGAVSPTGIKNEKRGTSPVTQVKDET 420 421 TAQPLNLSSRPKTAEPVKSPTSPTQNLFPASKTSPVNLPNKSSIPSPIGGSLGRGSSLDI 480 481 LSSLNSPALFGDQDTVMKAIQEARKMREQIQREQQQQPHGVDGKLSSMNNMGLSNCRTEK 540 541 ERTRFENLGPQLTGKSSEDGKLGPGVIDLTRPEDAEGSKAMNGSAAKLQQYYCWPTGGAT 600 601 VAEARVYRDARGRASSEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKS 660 661 MSNQEKQPYYEEQARLSKIHLEKYPNYKYKPRPKRTCIVDGKKLRIGEYKQLMRSRRQEM 720 721 RQFFTVGQQPQMPITTGTGVVYPGAITMATTTPSPQMTSDCSSTSASPEPSLPVIQSTYG 780 781 MKMDGASLAGNDMINGEDEMEAYDDYEDDPKSDYSSENEAPEPVSAN |
| Interface Residues: | 622, 625, 627, 628, 629, 631, 635, 646, 647, 648, 651, 689 |
| 3D-footprint Homologues: | 2lef_A, 4y60_C, 1o4x_B, 3f27_D, 6jrp_D, 1qrv_A, 3u2b_C, 7m5w_A, 2gzk_A, 4s2q_D, 1j5n_A, 1ckt_A, 1hry_A |
| Binding Motifs: | MA0515.1 cCwTTGTyyy |
| Binding Sites: | MA0515.1.1 MA0515.1.10 MA0515.1.11 MA0515.1.12 MA0515.1.13 MA0515.1.14 MA0515.1.15 MA0515.1.16 MA0515.1.17 MA0515.1.18 MA0515.1.19 MA0515.1.2 MA0515.1.20 MA0515.1.3 MA0515.1.4 MA0515.1.5 MA0515.1.6 MA0515.1.7 MA0515.1.8 MA0515.1.9 |
| Publications: | An C.I, Dong Y, Hagiwara N. Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6. BMC developmental biology 11:59 (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.