Transcription Factor
| Accessions: | T073408_1.02 (CISBP 1.02), O45080 (JASPAR 2024) |
| Names: | ceh-48, T073408_1.02;, O45080_CAEEL |
| Organisms: | Caenorhabditis elegans |
| Libraries: | CISBP 1.02 1, JASPAR 2024 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | experiment type:PBM, family:CUT,Homeodomain |
| Length: | 459 |
| Pfam Domains: | 221-299 CUT domain 322-375 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MDALTDSGSDPLLSAALGSPIHHAILSMDDEVDGNCDDVDDISPESHHDNHFIDFTDDLV 60 61 VQTERNLSKKGRTSNRNARQGYDNYATLTNLQPLPPISTVTSKSTKVQRPSPSPNFYFPT 120 121 SSNSSYDMKYEEEEDDCEGITHSSSSPSDFSNHGTDLNHPFSASSFDSFDVTTVSTTATS 180 181 TIMNSTDKFIARIQEADSTTKSPKGTSPAALMHGHCEEDFDDGEELNTKELALQIAAELK 240 241 RYSIPQAIFAERVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMAKWLEEPEFQRMSALR 300 301 LAACKRKEEHTTPNSPQMVVPKKTRLVFSDIQRRTLQAIFRETKRPSREMQITISQQLNL 360 361 DPTTVANFFMNARRRGHDLKQETSESEERSEEPSIHFEHSASSSSASSSSSSSMQLDNYI 420 421 CDINTINILEEPSPEPREIKYSMQLLENELDFPANILEP |
| Interface Residues: | 220, 221, 224, 225, 250, 251, 252, 255, 256, 257, 258, 260, 262, 263, 266, 270, 296, 322, 323, 324, 325, 366, 367, 370, 371, 374, 375, 376, 377, 378, 380 |
| 3D-footprint Homologues: | 6ymv_A, 1au7_A, 2d5v_B, 2o4a_A, 2h1k_B, 1jgg_B, 1nk2_P, 3l1p_A, 5hod_A, 1e3o_C, 8g87_X, 6fqp_B, 4qtr_D, 6fqq_E, 4xrm_B, 1o4x_A |
| Binding Motifs: | M0586_1.02 rayCrATaw MA0921.1 rayCrATaw MA0921.2 yCrAT |
| Publications: | Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed] Contrino S, Smith RN, Butano D, Carr A, Hu F, Lyne R, Rutherford K, Kalderimis A, Sullivan J, Carbon S, Kephart ET, Lloyd P, Stinson EO, Washington NL, Perry MD, Ruzanov P, Zha Z, Lewis SE, Stein LD, Micklem G. modMine: flexible access to modENCODE data. Nucleic Acids Res : (2012). [Pubmed] |
| Related annotations: | PaperBLAST |
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