Transcription Factor
| Accessions: | 1k78_F (3D-footprint 20231221), 3wtx_C (3D-footprint 20231221) |
| Names: | C-ets-1 Protein, ETS1_MOUSE, p54, Protein C-ets-1, ETS1_HUMAN |
| Organisms: | Mus musculus, Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P27577 |
| Length: | 103 |
| Pfam Domains: | 2-83 Ets-domain |
| Sequence: (in bold interface residues) | 1 PIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGL 60 61 RYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVK |
| Interface Residues: | 32, 36, 37, 40, 54, 55, 57, 58, 59, 61, 62, 76 |
| 3D-footprint Homologues: | 2wbs_A, 7jsa_J, 3zp5_A, 2stt_A, 8ee9_F, 4mhg_A, 1dux_F, 4uno_A, 3jtg_A, 4l18_B, 1yo5_C, 1awc_A, 4lg0_B, 4bqa_A, 1bc8_C, 4iri_A |
| Binding Motifs: | 1k78_EF CGGAGAnnnGnnnnanngG 3wtx_AC GCCACATCCT |
| Binding Sites: | 1k78_G 1k78_H 3wtx_D 3wtx_E 1k78_D |
| Publications: | Garvie C. W., Hagman J., Wolberger C. Structural studies of Ets-1/Pax5 complex formation on DNA.. Mol. Cell 8:1267-1276 (2001). [Pubmed] Shiina M, Hamada K, Inoue-Bungo T, Shimamura M, Uchiyama A, Baba S, Sato K, Yamamoto M, Ogata K. A Novel Allosteric Mechanism on Protein-DNA Interactions underlying the Phosphorylation-Dependent Regulation of Ets1 Target Gene Expressions. Journal of molecular biology 427:1655-69 (2015). [Pubmed] |
| Related annotations: | PaperBLAST |
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