Transcription Factor
| Accessions: | SOX3_MOUSE (HOCOMOCO 10), P53784 (JASPAR 2024) |
| Names: | SOX3_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P53784 |
| Length: | 375 |
| Pfam Domains: | 68-129 Domain of unknown function (DUF1898) 69-137 HMG (high mobility group) box 138-231 SOX transcription factor |
| Sequence: (in bold interface residues) | 1 MYSLLETELKNPVGPPTPAAGTGVPAAPGAAGKSGANPAGGANAGNGGSGGANGGGGGGG 60 61 GGGSDQDRVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEKRPFID 120 121 EAKRLRAVHMKEYPDYKYRPRRKTKTLLKKDKYSLPGGLLPPGAAAAAAAAAAAAAASSP 180 181 VGVGQRLDTYTHVNGWANGAYSLVQEQLGYAQPPSMSSPPPPPALPQMHRYDMAGLQYSP 240 241 MMPPGAQSYMNAAAAAAAASGYGGMAPSAAAAAAAAYGQQPATAAAAAAAAAAMSLGPMG 300 301 SVVKSEPSSPPPAIASHSQRACLGDLRDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQ 360 361 GAGTAVNGTVPLTHI |
| Interface Residues: | 71, 74, 76, 77, 78, 80, 84, 95, 96, 97, 100, 138, 142, 185 |
| 3D-footprint Homologues: | 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 3tq6_B, 1ckt_A, 1hry_A |
| Binding Motifs: | MA0514.1 CCTTTGTyyy SOX3_MOUSE.H10MO.C|M01347 kCCWTTGTbyy MA0514.2 raACAATGgma MA0514.3 ACAATGg |
| Binding Sites: | MA0514.3.12 MA0514.1.1 MA0514.1.10 MA0514.1.11 MA0514.1.12 MA0514.1.13 MA0514.1.14 MA0514.1.15 MA0514.1.16 MA0514.1.17 MA0514.1.18 MA0514.1.19 MA0514.1.2 MA0514.1.20 MA0514.1.3 MA0514.1.4 MA0514.1.5 MA0514.1.6 MA0514.1.7 MA0514.1.8 MA0514.1.9 MA0514.2.1 / MA0514.2.2 MA0514.2.10 / MA0514.2.17 MA0514.2.11 / MA0514.2.18 MA0514.2.12 MA0514.2.13 / MA0514.2.20 MA0514.2.14 MA0514.2.15 / MA0514.2.16 MA0514.2.17 MA0514.2.18 MA0514.2.19 MA0514.2.2 / MA0514.2.5 MA0514.2.20 MA0514.2.3 / MA0514.2.6 MA0514.2.4 / MA0514.2.7 MA0514.2.5 MA0514.2.6 / MA0514.2.9 MA0514.2.11 / MA0514.2.7 MA0514.2.13 / MA0514.2.8 MA0514.2.16 / MA0514.2.9 MA0514.3.11 / MA0514.3.13 / MA0514.3.15 / MA0514.3.16 / MA0514.3.19 / MA0514.3.8 MA0514.3.1 / MA0514.3.10 / MA0514.3.4 / MA0514.3.6 MA0514.3.18 / MA0514.3.2 / MA0514.3.20 / MA0514.3.3 MA0514.3.17 / MA0514.3.9 MA0514.2.1 MA0514.2.10 MA0514.2.12 MA0514.2.14 MA0514.2.15 MA0514.2.19 MA0514.2.3 MA0514.2.4 MA0514.2.8 MA0514.3.14 MA0514.3.5 MA0514.3.7 |
| Publications: | Collignon J., Sockanathan S., Hacker A., Cohen-Tannoudji M., Norris D., Rastan S., Stevanovic M., Goodfellow P. N., Lovell-Badge R. A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2. Development 122:509-520 (1996). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.