Transcription Factor

Accessions: 4kdp_A (3D-footprint 20210203), 4kdp_B (3D-footprint 20210203)
Names: A0A0H2VJZ8_STAES, TcaR transcription regulator
Organisms: strain ATCC 12228 / FDA PCI 1200, Staphylococcus epidermidis
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q8CN94
Length: 151
Pfam Domains: 34-93 MarR family
37-93 MarR family
37-103 Winged helix DNA-binding domain
42-82 Bacterial regulatory protein, arsR family
Sequence:
(in bold interface residues)
1 MVRRIEDHISFLEKFINDVNTLTAKLLKDLQTEYGISAEQSHVLNMLSIEALTVGQITEK 60
61 QGVNKAAVSRRVKKLLNAELVKLEKPDSNTDQRLKIIKLSNKGKKYIKERKAIMSHIASD 120
121 MTSDFDSKEIEKVRQVLEIIDYRIQSYTSKL
Interface Residues: 37, 39, 64, 65, 66, 67, 69, 70, 71, 74, 93
3D-footprint Homologues: 4kdp_B, 3q5f_A, 5yi2_J
Binding Motifs: 4kdp_AB CGCAGcGnnnA
4kdp_B CncAg
Binding Sites: 4kdp_H
Publications: Chang Y.M, Ho C.H, Chen C.K, Maestre-Reyna M, Chang-Chien M.W, Wang A.H. TcaR-ssDNA complex crystal structure reveals new DNA binding mechanism of the MarR family proteins. Nucleic acids research 42:5314-21 (2014). [Pubmed]
Related annotations: PaperBLAST

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