Transcription Factor

Accessions: Q12457 (JASPAR 2024)
Names: NSI1_YEAST, NTS1 silencing protein 1, RNA polymerase I termination factor
Organisms: Saccharomyces cerevisiae S288c, Saccharomyces cerevisiae
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 570
Pfam Domains: 345-389 Myb-like DNA-binding domain
348-408 Myb-like DNA-binding domain
398-485 Myb-like DNA-binding domain
Sequence:
(in bold interface residues)
1 MDSVSNLKSTNFQNNNDPKESVEEAVLRYVGVDLKNHIKKTKKKLKKQKKRKHGSKMSHE 60
61 DEDTDMDWYLKTSGSKDLRKVDDIEPNSVAVAAVAAAYNSSMREKDKRSCHKKSSNSRSE 120
121 RKKHRKRKSSKERKAKIKMVLDPQLTTLDDGITTTAFLPDDLIAETAFDKYVDTEKAYLA 180
181 KHPSKSLEVNEDDKENNFNNNSSTLVRIYTDLEGIPNDGSYIKRTPKIPEKDVKSDDLIL 240
241 APEENNGDTALLRSDIVKASVIDGAITKSIGKKFTPSEENALDQFIEEYMKIRGLDRRQM 300
301 CERIWSTDGVIRDGFWANISKVLPYRTRSSIYKHIRRKYHIFEQRGKWTPEEDQELARLC 360
361 LEKEGHWTEVGKLLGRMPEDCRDRWRNYMKCGSKRGSKRWSKEEEELLTTVVNEMIEEAH 420
421 QYQRMKALEAANKNDRYNQMYSRGPKGKRISDNPTFKDMINWTVVSERMSGTRSRIQCRY 480
481 KWNKLVTDEAARSMLSIPVSERKWLLERLKQLPKTSYSNIDWNSIATYKPGYPRTGLELR 540
541 LCYEQMREKIHDFKGRSTAEIIDSLLEQIN
Interface Residues: 328, 329, 332, 333, 336, 337, 377, 378, 379, 380, 382, 383, 386, 387, 388, 475, 476, 479, 480
3D-footprint Homologues: 3zqc_A, 5eyb_B, 2kdz_A, 6kks_A, 3osg_A, 1mse_C
Binding Motifs: MA0421.1 TTTACCCGGm
Publications: Pachkov M, Erb I, Molina N, van Nimwegen E. SwissRegulon: a database of genome-wide annotations of regulatory sites. Nucleic acids research 35:D127-31 (2007). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.