Transcription Factor
| Accessions: | KAISO_HUMAN (HOCOMOCO 10), Q86T24 (JASPAR 2024) |
| Names: | KAISO_HUMAN, Transcriptional regulator Kaiso, Zinc finger and BTB domain-containing protein 33 |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q86T24 |
| Length: | 672 |
| Pfam Domains: | 22-114 BTB/POZ domain 508-531 Zinc-finger double domain 538-560 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQL 60 61 FSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPL 120 121 SQVKSISGTAQDGNTEPLPPDSGDKNLVIQKSKDEAQDNGATIMPIITESFSLSAEDYEM 180 181 KKIIVTDSDDDDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVAISDVAPSASNNSPPL 240 241 TNITPTQKLPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLSTPPNVSSSLPN 300 301 HMPSSINLLVQNQQTPNSAILTGNKANEEEEEEIIDDDDDTISSSPDSAVSNTSLVPQAD 360 361 TSQNTSFDGSLIQKMQIPTLLQEPLSNSLKISDIITRNTNDPGVGSKHLMEGQKIITLDT 420 421 ATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDEGEARLENEIPKTSGSEMANKRMKVKH 480 481 DDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKH 540 541 EIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCRSLQIRQYAYL 600 601 SDRSSTIPAMKDDGIGYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDG 660 661 STEFEFIIPESY |
| Interface Residues: | 466, 469, 472, 474, 475, 476, 477, 478, 479, 504, 505, 506, 507, 508, 510, 511, 513, 514, 517, 531, 532, 533, 534, 535, 536, 537, 538, 539, 540, 543, 560, 561, 562, 563, 564, 565, 566, 567, 568, 571, 595, 597 |
| 3D-footprint Homologues: | 5kkq_D, 6wmi_A, 2i13_A, 2lt7_A, 7n5w_A, 6jnm_A, 1tf3_A, 6ml4_A, 2gli_A, 1g2f_F, 6blw_A, 1tf6_A, 6u9q_A, 4x9j_A, 6e94_A, 5kl3_A, 1ubd_C, 7ysf_A, 5ei9_F, 1mey_C, 5und_A, 2drp_D, 7eyi_G, 5k5i_A, 2kmk_A, 8h9h_G, 5v3j_F, 6a57_A, 2jpa_A, 7w1m_H, 3uk3_C, 8cuc_F, 7y3l_A, 5yel_A, 1llm_D, 7txc_E, 2wbs_A, 8ssq_A, 1f2i_J, 4m9v_C, 7y3m_I, 8gn3_A, 5yj3_D |
| Binding Motifs: | MA0527.1 yTCTCGCGakayyts KAISO_HUMAN.H10MO.A|M01284 gtTctCGCGAGrstysggs MA0527.2 TCTCGCGaka |
| Binding Sites: | MA0527.1.1 MA0527.1.10 MA0527.1.11 MA0527.1.12 / MA0527.1.7 MA0527.1.13 MA0527.1.14 MA0527.1.15 MA0527.1.16 MA0527.1.17 MA0527.1.18 MA0527.1.19 MA0527.1.2 MA0527.1.20 MA0527.1.3 MA0527.1.4 MA0527.1.5 MA0527.1.6 MA0527.1.8 MA0527.1.9 MA0527.2.1 MA0527.2.10 MA0527.2.11 MA0527.2.12 MA0527.2.13 MA0527.2.14 MA0527.2.15 MA0527.2.16 MA0527.2.17 MA0527.2.18 MA0527.2.19 MA0527.2.2 MA0527.2.20 MA0527.2.3 MA0527.2.4 MA0527.2.5 MA0527.2.6 MA0527.2.7 MA0527.2.8 MA0527.2.9 |
| Publications: | Blattler A, Yao L, Wang Y, Ye Z, Jin V.X, Farnham P.J. ZBTB33 binds unmethylated regions of the genome associated with actively expressed genes. Epigenetics & chromatin 6:13 (2013). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.