Transcription Factor
| Accessions: | Q94FL9 (JASPAR 2024), T21882 (AthalianaCistrome v4_May2016) |
| Names: | MB3R4_ARATH, Myb-related protein 3R-4, Protein ENHANCED DEFECTIVE CYTOKINESIS, Transcription factor MYB3R-4, AT5G11510, MYB3R4, T21882; |
| Organisms: | Arabidopsis thaliana |
| Libraries: | JASPAR 2024 1, AthalianaCistrome v4_May2016 2 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] 2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed] |
| Notes: | ecotype:Col-0, experiment type: DAP-seq, family:MYB |
| Length: | 961 |
| Pfam Domains: | 29-75 Myb-like DNA-binding domain 32-91 Myb-like DNA-binding domain 81-127 Myb-like DNA-binding domain 84-142 Myb-like DNA-binding domain 133-175 Myb-like DNA-binding domain 136-181 Myb-like DNA-binding domain |
| Sequence: (in bold interface residues) | 1 MEAESSTPQERIPKLRHGRTSGPARRSTRGQWTAEEDEILRKAVHSFKGKNWKKIAEYFK 60 61 DRTDVQCLHRWQKVLNPELVKGPWTKEEDEMIVQLIEKYGPKKWSTIARFLPGRIGKQCR 120 121 ERWHNHLNPAINKEAWTQEEELLLIRAHQIYGNRWAELTKFLPGRSDNGIKNHWHSSVKK 180 181 KLDSYMSSGLLDQYQAMPLAPYERSSTLQSTFMQSNIDGNGCLNGQAENEIDSRQNSSMV 240 241 GCSLSARDFQNGTINIGHDFHPCGNSQENEQTAYHSEQFYYPELEDISVSISEVSYDMED 300 301 CSQFPDHNVSTSPSQDYQFDFQELSDISLEMRHNMSEIPMPYTKESKESTLGAPNSTLNI 360 361 DVATYTNSANVLTPETECCRVLFPDQESEGHSVSRSLTQEPNEFNQVDRRDPILYSSASD 420 421 RQISEATKSPTQSSSSRFTATAASGKGTLRPAPLIISPDKYSKKSSGLICHPFEVEPKCT 480 481 TNGNGSFICIGDPSSSTCVDEGTNNSSEEDQSYHVNDPKKLVPVNDFASLAEDRPHSLPK 540 541 HEPNMTNEQHHEDMGASSSLGFPSFDLPVFNCDLLQSKNDPLHDYSPLGIRKLLMSTMTC 600 601 MSPLRLWESPTGKKTLVGAQSILRKRTRDLLTPLSEKRSDKKLEIDIAASLAKDFSRLDV 660 661 MFDETENRQSNFGNSTGVIHGDRENHFHILNGDGEEWSGKPSSLFSHRMPEETMHIRKSL 720 721 EKVDQICMEANVREKDDSEQDVENVEFFSGILSEHNTGKPVLSTPGQSVTKAEKAQVSTP 780 781 RNQLQRTLMATSNKEHHSPSSVCLVINSPSRARNKEGHLVDNGTSNENFSIFCGTPFRRG 840 841 LESPSAWKSPFYINSLLPSPRFDTDLTIEDMGYIFSPGERSYESIGVMTQINEHTSAFAA 900 901 FADAMEVSISPTNDDARQKKELDKENNDPLLAERRVLDFNDCESPIKATEEVSSYLLKGC 960 961 R |
| Interface Residues: | 29, 64, 65, 68, 69, 72, 73, 81, 115, 116, 117, 118, 120, 121, 125, 126, 167, 168, 171, 172, 175, 176, 177, 601, 612, 613, 616, 617, 620, 621, 624 |
| 3D-footprint Homologues: | 7c4r_A, 1w0t_A, 5eyb_B, 7xur_A, 1vfc_A, 3osg_A, 2kdz_A, 6kks_A, 3zqc_A, 1mse_C, 5gzb_A |
| Binding Motifs: | M0543 / MA1180.1 wwwwaTrrCCGTTrr MA1180.2 wwaTrrCCGTTr |
| Binding Sites: | MA1180.1.2 MA1180.1.17 MA1180.1.19 MA1180.1.12 MA1180.1.1 / MA1180.1.3 MA1180.1.18 MA1180.1.10 MA1180.1.8 / MA1180.1.9 MA1180.1.7 MA1180.1.5 MA1180.1.15 MA1180.1.11 MA1180.1.13 MA1180.1.14 MA1180.1.16 MA1180.1.20 MA1180.1.4 MA1180.1.6 MA1180.2.1 / MA1180.2.3 MA1180.2.10 MA1180.2.11 MA1180.2.12 MA1180.2.13 MA1180.2.14 MA1180.2.15 MA1180.2.16 MA1180.2.17 MA1180.2.18 MA1180.2.19 MA1180.2.2 MA1180.2.20 MA1180.2.4 MA1180.2.5 MA1180.2.6 MA1180.2.7 MA1180.2.8 / MA1180.2.9 |
| Publications: | Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] |
| Related annotations: | PaperBLAST |
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