Transcription Factor
| Accessions: | Q61670 (JASPAR 2024) |
| Names: | H2.0-like homeobox protein, HLX_MOUSE, Homeobox protein HLX1 |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 476 |
| Pfam Domains: | 276-330 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MFAAGLAPFYASNFSLWSAAYCSSAGPGGCSFALDPAAVKKPSFCIADILHAGVGEPGPA 60 61 AEGLVGASAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAFHQ 120 121 HLPQQSPTQQQQPQQQPPPPPRAVSLQPPTSGTRVVPHHSGSAPAPSSKDLKFGIDRILS 180 181 AEFDPKVKEGNTLRDLTSLLTGGRPAGVHLAGLQPSAGQFFASLDPISEASAILSPLSSN 240 241 PRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTK 300 301 PDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGVPAEGEREE 360 361 RSPSRSEGEAESESSDSESLDMAPSDTERTEGTERSLHQTTVIKASAAGALITASSSTSG 420 421 SSFSFSSTSSLGSGNTHVGSASSLGGNCSELPSAHQPSVTSSPQSPEIAQAPLAGL |
| Interface Residues: | 271, 272, 273, 274, 275, 276, 277, 315, 316, 318, 319, 322, 323, 326, 327, 329, 330, 333 |
| 3D-footprint Homologues: | 3d1n_M, 1au7_A, 1nk2_P, 3l1p_A, 1puf_A, 6m3d_C, 7q3o_C, 6es3_K, 2r5y_A, 5flv_I, 2hos_A, 5zjt_E, 3a01_E, 2d5v_B, 1jgg_B, 7psx_B, 3lnq_A, 2ld5_A, 3cmy_A, 2h1k_B, 5jlw_D, 3rkq_B, 2lkx_A, 1fjl_B, 4xrs_G, 2hdd_A, 1b72_A, 4cyc_A, 1ig7_A, 1e3o_C, 1le8_A, 1zq3_P, 1o4x_A, 1du0_A, 4qtr_D, 5hod_A, 6a8r_A, 4xrm_B, 1puf_B, 8g87_X, 5zfz_A |
| Binding Motifs: | PH0038.1 cmaTAATTrATTAym |
| Publications: | Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.