Transcription Factor
| Accessions: | P36197 (JASPAR 2024) |
| Names: | Delta EF1, Delta-crystallin enhancer-binding factor, TCF-8, Transcription factor 8, ZEB1_CHICK, Zinc finger E-box-binding homeobox 1 |
| Organisms: | chick, Gallus gallus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 1115 |
| Pfam Domains: | 171-193 C2H2-type zinc finger 171-193 Zinc finger, C2H2 type 184-211 Zinc-finger double domain 200-223 Zinc-finger of C2H2 type 200-222 C2H2-type zinc finger 215-251 Zinc-finger double domain 240-262 C2H2-type zinc finger 240-262 Zinc finger, C2H2 type 254-279 Zinc-finger double domain 268-291 Zinc-finger of C2H2 type 268-288 C2H2-type zinc finger 268-289 Zinc finger, C2H2 type 592-630 Homeobox domain 904-926 Zinc finger, C2H2 type 904-926 C2H2-type zinc finger 918-943 Zinc-finger double domain 932-954 Zinc finger, C2H2 type 932-954 C2H2-type zinc finger 947-971 Zinc-finger double domain 960-980 C2H2-type zinc finger 960-980 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MADGPRCKRRKQANPRRNNVTNYNNVIEANSDSDDEDKLHIVEEESITDAADCDASVPED 60 61 DLPTDHTVLPENSEREGSTNSCWEDEGKETKEILGPEAQSDEVGCTVKEDECDSDAENEQ 120 121 NHDPNVEEFLQQEDTAVIYPEAPEEDQRQGTPEASGQDENGTPDAFSQLLTCPYCDRGYK 180 181 RFTSLKEHIKYRHEKNEDNFSCSLCSYTFAYRTQLDRHMTSHKSGRDQRHVTQSSGNRKF 240 241 KCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCIGLMPVKG 300 301 RARSGLKTSQCSSPSLSASPGSPARPQIRQKIENKPLQEQLPVNQIKTEPVDYEFKPIVV 360 361 ASGINCSTPLQNGVFSGGSPLQATSSPQGVVQAVVLPTVGLVSPISINLSDIQNVLKVAV 420 421 DGNVIRQVLENNHANLASKEQETISNASIQQAGHSLISAISLPLVDQDGTTKIIINYSLE 480 481 QPSQLQVVPQNLKKEHSVPTNSCKNEKLPEDLTVKSEKDKNFEGETNDSTCLLCDDCPGD 540 541 LNALQELKHYETKNPPQLPQSSGTEAEKPSSPAPSETGENNLSPGQPPLKNLLSLLKAYY 600 601 ALNAQPSAEELSKIADSVNLPLDVVKKWFEKMQAGQISVQSSGPSSPEQVKISSPTDNDD 660 661 QAATTNESEPQNSTNNSQNPANTSKSQTSSGGSTQNGSRSSTPSPSPLNLSSSRNSQGYT 720 721 YTAEGVQEEPQMEPLDLSLPKQHGELLERSTITSVYQNSVYSVQEEPLNLTCAKKEPQKD 780 781 NSITDSDPIVNVIPPSANPINIAIPTVTAQLPTIVAIADQNSVPCLRALAANKQTILIPQ 840 841 VAYTYSTTVSPAVQETPPKQTQANGSQDERQDTSSEGVSNVEDQNDSDSTPPKKKMRKTE 900 901 NGMYACDLCDKIFQKSSSLLRHKYEHTGKRPHECGICKKAFKHKHHLIEHMRLHSGEKPY 960 961 QCDKCGKRFSHSGSYSQHMNHRYSYCKREAEERDSTEQEEVGQEVLSSEHAGARAS PSQ 1020 1021 IDSDERESLTREEEEDSEKEEEEEEEKDVEGLQEEKECRKLQDVEEEEEVEEEEEEEEGK 1080 1081 TEGNKNDDVVNRASNAEPEVIQSNGQVSEEKTNKA |
| Interface Residues: | 181, 182, 183, 184, 187, 191, 211, 213, 214, 217, 250, 251, 252, 253, 254, 257, 279, 281, 282, 284, 285, 626, 627, 904, 914, 915, 916, 917, 918, 920, 921, 922, 942, 943, 944, 945, 946, 947, 948, 949, 950, 970, 971, 972, 973, 974, 976, 977, 982, 985 |
| 3D-footprint Homologues: | 5k5l_F, 8ssq_A, 5kkq_D, 8ssu_A, 5yel_A, 7w1m_H, 1ubd_C, 8gn3_A, 8cuc_F, 3uk3_C, 2drp_D, 5yj3_D, 5k5i_A, 2xsd_C, 7xrc_C, 1au7_A, 3d1n_M, 1o4x_A, 2kmk_A, 1tf3_A, 7n5w_A, 6jnm_A, 1g2f_F, 6ml4_A, 4x9j_A, 6blw_A, 2gli_A, 6u9q_A, 5ei9_F, 1tf6_A, 5kl3_A, 2i13_A, 1mey_C, 6wmi_A, 1f2i_J, 5und_A, 2jpa_A, 7ysf_A, 5v3j_F, 8h9h_G, 4m9v_C, 7eyi_G, 2lt7_A, 6e94_A, 6a57_A, 7y3l_A, 1llm_D, 7txc_E, 2wbs_A, 7y3m_I |
| Binding Motifs: | MA0103.1 CACCTk |
| Binding Sites: | MA0103.1.1 MA0103.1.10 MA0103.1.11 MA0103.1.12 MA0103.1.13 MA0103.1.14 MA0103.1.15 MA0103.1.16 MA0103.1.17 MA0103.1.18 MA0103.1.19 MA0103.1.2 MA0103.1.20 MA0103.1.3 / MA0103.1.4 MA0103.1.5 MA0103.1.6 MA0103.1.7 MA0103.1.8 MA0103.1.9 |
| Publications: | Sekido R., Murai K., Funahashi J.-i., Kamachi Y., Fujisawa-Sehara A., Nabeshima Y.-I., Kondoh H. The delta-crystallin enhancer-binding protein deltaEF1 is a repressor of E2-box-mediated gene activation. Mol. Cell. Biol. 14:5692-5700 (1994). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.