Transcription Factor

						

			
Accessions: MYC2 (Athamap 20091028), T012373_1.02 (CISBP 1.02), Q39204 (JASPAR 2024)

			
Names: AtbHLH6, AtMYC2, Basic helix-loop-helix protein 6, bHLH 6, bHLH transcription factor bHLH006, bHLH6, JIN1, MYC2, Protein JASMONATE INSENSITIVE 1, R-homologous Arabidopsis protein 1, RAP-1, RAP1, rd22BP1, Transcription factor EN 38, Transcription factor MYC2, Z-box binding factor 1 protein, ZBF1, T012373_1.02;, MYC2_ARATH
Organisms: Arabidopsis thaliana
Libraries: Athamap 20091028 1, CISBP 1.02 2, JASPAR 2024 3
1 Bulow L, Engelmann S, Schindler M, Hehl R. AthaMap, integrating transcriptional and post-transcriptional data. Nucleic acids research 37:D983-6 (2009).  [Pubmed]

2 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]

3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q39204
Notes: experiment type:PBM, family:bHLH
Length: 623
Pfam Domains:    68-252 bHLH-MYC and R2R3-MYB transcription factors N-terminal
  452-497 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 MTDYRLQPTMNLWTTDDNASMMEAFMSSSDISTLWPPASTTTTTATTETTPTPAMEIPAQ   60
  61 AGFNQETLQQRLQALIEGTHEGWTYAIFWQPSYDFSGASVLGWGDGYYKGEEDKANPRRR  120
 121 SSSPPFSTPADQEYRKKVLRELNSLISGGVAPSDDAVDEEVTDTEWFFLVSMTQSFACGA  180
 181 GLAGKAFATGNAVWVSGSDQLSGSGCERAKQGGVFGMHTIACIPSANGVVEVGSTEPIRQ  240
 241 SSDLINKVRILFNFDGGAGDLSGLNWNLDPDQGENDPSMWINDPIGTPGSNEPGNGAPSS  300
 301 SSQLFSKSIQFENGSSSTITENPNLDPTPSPVHSQTQNPKFNNTFSRELNFSTSSSTLVK  360
 361 PRSGEILNFGDEGKRSSGNPDPSSYSGQTQFENKRKRSMVLNEDKVLSFGDKTAGESDHS  420
 421 DLEASVVKEVAVEKRPKKRGRKPANGREEPLNHVEAERQRREKLNQRFYALRAVVPNVSK  480
 481 MDKASLLGDAIAYINELKSKVVKTESEKLQIKNQLEEVKLELAGRKASASGGDMSSSCSS  540
 541 IKPVGMEIEVKIIGWDAMIRVESSKRNHPAARLMSALMDLELEVNHASMSVVNDLMIQQA  600
 601 TVKMGFRIYTQEQLRASLISKIG
Interface Residues: 453, 454, 456, 457, 460, 461, 465, 481, 483
3D-footprint Homologues: 7ssa_L, 5gnj_I, 6g1l_A, 4h10_A, 7xi3_A, 5i50_B, 7d8t_A, 4zpk_A, 7xq5_A, 5nj8_D, 7rcu_E, 5eyo_A, 5v0l_A, 8osl_P, 1an4_A
Binding Motifs: MYC2 TGACACGT
MA0566.1 rCACGTGy
M0152_1.02 mrCACGTGyk
Binding Sites: MYC2_1
MYC2_2
			
Publications: Yadav V, Mallappa C, Gangappa SN, Bhatia S, Chattopadhyay S. 2005. A basic helix-loop-helix transcription factor in Arabidopsis, MYC2, acts as a repressor of blue light-mediated photomorphogenic growth. Plant Cell 17: 1953-66. [Pubmed]


Godoy M, Franco-Zorrilla J.M, Pérez-Pérez J, Oliveros J.C, Lorenzo O, Solano R. Improved protein-binding microarrays for the identification of DNA-binding specificities of transcription factors. The Plant journal : for cell and molecular biology 66:700-11 (2011). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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