Transcription Factor
| Accessions: | P10180 (JASPAR 2024) |
| Names: | CUT_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 2177 |
| Pfam Domains: | 881-957 CUT domain 1332-1414 CUT domain 1614-1693 CUT domain 1746-1802 Homeobox domain 1767-1799 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 MQPTLPQAAGTADMDLTAVQSINDWFFKKEQIYLLAQFWQQRATLAEKEVNTLKEQLSTG 60 61 NPDSNLNSENSDTAAAAATAAAVAAVVAGATATNDIEDEQQQQLQQTASGGILESDSDKL 120 121 LNSSIVAAAITLQQQNGSNLLANTNTPSPSPPLLSAEQQQQLQSSLQQSGGVGGACLNPK 180 181 LFFNHAQQMMMMEAAAAAAAAALQQQQQQQSPLHSPANEVAIPTEQPAATVATGAAAAAA 240 241 AAATPIATGNVKSGSTTSNANHTNSNNSHQDEEELDDEEEDEEEDEDEDDEEENASMQSN 300 301 ADDMELDAQQETRTEPSATTQQQHQQQDTEDLEENKDAGEASLNVSNNHNTTDSNNSCSR 360 361 KNNNGGNESEQHVASSAEDDDCANNNTNTSNNNNTSNTATSNTNNNNNNNSSSGNSEKRK 420 421 KKNNNNNNGQPAVLLAAKDKEIKALLDELQRLRAQEQTHLVQIQRLEEHLEVKRQHIIRL 480 481 EARLDKQQINEALAEATALSAAASTNNNNNSQSSDNNKKLNTAAERPMDASSNADLPEST 540 541 KAPVPAEDDEEDEDQAMLVDSEEAEDKPEDSHHDDDEDEDEDREAVNATTTDSNELKIKK 600 601 EQHSPLDLNVLSPNSAIAAAAAAAAAAACANDPNKFQALLIERTKALAAEALKNGASDAL 660 661 SEDAHHQQQQHHQQQHQHQQQHHQQQHLHQQHHHHLQQQPNSGSNSNPASNDHHHGHHLH 720 721 GHGLLHPSSAHHLHHQTTESNSNSSTPTAAGNNNGSNNSSSNTNANSTAQLAASLASTLN 780 781 GTKSLMQEDSNGLAAVAMAAHAQHAAALGPGFLPGLPAFQFAAAQVAAGGDGRGHYRFAD 840 841 SELQLPPGASMAGRLGESLIPKGDPMEAKLQEMLRYNMDKYANQALDTLHISRRVRELLS 900 901 VHNIGQRLFAKYILGLSQGTVSELLSKPKPWDKLTEKGRDSYRKMHAWACDDNAVMLLKS 960 961 LIPKKDSGLPQYAGRGAGGAGGDDSMSEDRIAHILSEASSLMKQSSVAQHREQERRS HG 1020 1021 GEDSHSNEDSKSPPQSCTSPFFKVENQLKQHQHLNPEQAAAQQREREREQREREQQQRLR 1080 1081 HDDQDKMARLYQELIARTPRETAFPSFLFSPSLFGGAAGMPGAASNAFPAMADENMRHVF 1140 1141 EREIAKLQQHQQQQQAAQAQAQFPNFSSLMALQQQVLNGAQDLSLAAAAAKDIKLNGQRS 1200 1201 SLEHSAGSSSCSKDGERDDAYPSSLHGRKSEGGGTPAPPAPPSGPGTGAGAPPTAAPPTG 1260 1261 GASSNSAAPSPLSNSILPPALSSQGEEFAATASPLQRMASITNSLITQPPVTPHHSTPQR 1320 1321 PTKAVLPPITQQQFDMFNNLNTEDIVRRVKEALSQYSISQRLFGESVLGLSQGSVSDLLA 1380 1381 RPKPWHMLTQKGREPFIRMKMFLEDENAVHKLVASQYKIAPEKLMRTGSYSGSPQMPQGL 1440 1441 ASKMQAASLPMQKMMSELKLQEPAQAQHLMQQMQAAAMSAAMQQQQVAQAQQQAQQAQQA 1500 1501 QQHLQQQAQQHLQQQQHLAQQQHPHQQHHQAAAAAAALHHQSMLLTSPGLPPQHAISLPP 1560 1561 SAGGAQPGGPGGNQGSSNPSNSEKKPMLMPVHGTNAMRSLHQHMSPTVYEMAALTQDLDT 1620 1621 HDITTKIKEALLANNIGQKIFGEAVLGLSQGSVSELLSKPKPWHMLSIKGREPFIRMQLW 1680 1681 LSDANNVERLQLLKNERREASKRRRSTGPNQQDNSSDTSSNDTNDFYTSSPGPGSVGSGV 1740 1741 GGAPPSKKQRVLFSEEQKEALRLAFALDPYPNVGTIEFLANELGLATRTITNWFHNHRMR 1800 1801 LKQQVPHGPAGQDNPIPSRESTSATPFDPVQFRILLQQRLLELHKERMGMSGAPIPYPPY 1860 1861 FAAAAILGRSLAGIPGAAAAAGAAAAAAAVGASGGDELQALNQAFKEQMSGLDLSMPTLK 1920 1921 RERSDDYQDDLELEGGGHNLSDNESLEGQEPEDKTTDYEKVLHKSALAAAAAYMSNAVRS 1980 1981 SRRKPAAPQWVNPAGAVTNPSAVVAAVAAAAAAAADNERIINGVCVMQASEYGRDDTDSN 2040 2041 KP TDGGNDSDHEHAQLEIDQRFMEPEVHIKQEEDDDEEQSGSVNLDNEDNATSEQKLKV 2100 2101 INEEKLRMVRVRRLSSTGGGSSEEMPAPLAPPPPPPAASSSIVSGESTTSSSSSSNTSSS 2160 2161 TPAVTTAAATAAAGWNY |
| Interface Residues: | 1370, 1371, 1373, 1375, 1376, 1746, 1747, 1748, 1749, 1787, 1788, 1790, 1791, 1794, 1795, 1798, 1799, 1802, 1811 |
| 3D-footprint Homologues: | 2d5v_B, 6a8r_A, 3cmy_A, 2h1k_B, 1puf_A, 1fjl_B, 5zfz_A, 3lnq_A, 1nk2_P, 2lkx_A, 1jgg_B, 2ld5_A, 6es3_K, 7q3o_C, 5hod_A, 3rkq_B, 4xrs_G, 3d1n_M, 2hdd_A, 2r5y_A, 1puf_B, 7psx_B, 5flv_I, 3l1p_A, 2hos_A, 5zjt_E, 1au7_A, 5jlw_D, 7xrc_C, 2xsd_C, 4xrm_B, 1du0_A, 4cyc_A, 4qtr_D |
| Binding Motifs: | MA0218.1 YTrAAC |
| Binding Sites: | MA0218.1.1 MA0218.1.10 MA0218.1.11 MA0218.1.12 MA0218.1.13 MA0218.1.14 MA0218.1.15 MA0218.1.16 MA0218.1.17 MA0218.1.18 MA0218.1.19 MA0218.1.2 MA0218.1.20 MA0218.1.3 MA0218.1.4 MA0218.1.5 MA0218.1.6 MA0218.1.7 MA0218.1.8 MA0218.1.9 |
| Publications: | Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.